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1、中藥復(fù)方制劑治療冠狀動(dòng)脈粥樣硬化炎癥臨床觀察摘要：目的：應(yīng)用中藥復(fù)方制劑觀察冠心病患者的炎癥因子變化及探索清熱解毒中藥治療動(dòng)脈硬化性疾病的新思路。方法：將87例冠心病心絞痛（穩(wěn)定勞累）心功能1-2級(jí)、中醫(yī)分型熱瘀痰阻證的患者隨機(jī)分為辛伐他汀組（30例x復(fù)方丹參片組（27例X中藥復(fù)方制劑組（30例），觀察3組治療前后C■反應(yīng)蛋白、甘油三酯、膽固醇、高密度脂蛋白、低密度脂蛋白等指標(biāo)的變化。結(jié)果：治療后，中藥復(fù)方制劑組降C反應(yīng)蛋白（CRP血清總膽固醇（TCL低密度脂蛋白（LDL）的效果明顯優(yōu)于辛伐他汀片組與復(fù)方丹參片組（P<0.
2、05b結(jié)論：中藥復(fù)方制劑對(duì)冠狀動(dòng)脈粥樣硬化炎癥指標(biāo)的影響顯著，對(duì)冠狀動(dòng)脈炎癥有良好的療效。清熱解毒法作為冠心病一種新的治法或治法的補(bǔ)充，值得進(jìn)一步研究。關(guān)鍵詞：中藥；復(fù)方制劑；冠狀動(dòng)脈粥樣硬化；炎癥中圖分類號(hào)：R541.4文獻(xiàn)標(biāo)識(shí)碼：B文章編號(hào)：1673-7717(2011)12-2684-03ObservationonClinicalEffectofChineseCompoundPrescriptionTreatingCoronaryArteriesarteriosclerosisInflammatoryZHANGXin1
3、,WANGLianzhi2,SUXianhong3(1丄iaoningUniversityofTCM,Shenyang110847,Liaoning,China;2.ThirdAffilatedHospitalofLiaoningUniversityofTCM,Shenyang110003,Liaoning,China;3.SecondAffilatedHospitalofLiaoningUniversityofTCM,Shenyang110034,Liaoning,China)Abstract:Objective:Appl
4、yingChinesecompoundprescriptiontoobservethechangeofinflammatoryfactorforcoronaryheartdiseasepatientswithinflammatoryreactionandexploreanewwayoftreatingarteriosclerosiswithheat-clearinganddetoxifyingtraditionalChinesedrugs?Methods:Dividerandomly87casespatientsofcoro
5、naryheartdisease,angina(stabletiredness)cardiacfunction1~2grade,belongingtoheatbloodstasisandphlegmysyndromeintosimvastatingroup(30cases),compoundsalviatabletgroup(27cases)andChinesecompoundprescriptiongroup(30cases),andobserveindexessuchasc-reactiveprotein,triglyc
6、erideandcholesterol,high-densitylipoproteincholesterol,andlowdensitylipoprotein?Results:Aftertreatment,effectofc-reactiveprotein(CRP),serumtotalcholesterol(TC),lowdensitylipoprotein(LDL)ofChinesecompoundprescriptionisobviouslysuperiortosimvastatingroupandcompoundsa
7、lviatabletgroup(P<0.05)?Conclusion:Chinesecompoundprescriptionhasaremarkableinfluenceoncoronaryarteriosclerosisinflammatoryindexandhasagoodcurativeeffectoncoronaryarteriesarteriosclerosisinflammation.Methodofheat-clearinganddetoxifyingasanewtherapyorsupplementalthe
8、rapyisworthfutherstudying.Keywords:Chinesedrug;compoundprescription;coronaryarteriosclerosis;inflammation動(dòng)脈粥樣硬化所致的心、腦血管疾病是嚴(yán)重危害人民生命健康的疾病之一，其發(fā)病率和死亡
