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《人參 五靈脂配伍對(duì)人參補(bǔ)氣作用影響的初步藥效學(xué)研究》由會(huì)員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在行業(yè)資料-天天文庫(kù)。
1、人參五靈脂配伍對(duì)人參補(bǔ)氣作用影響的初步藥效學(xué)研究摘要:目的:利用現(xiàn)代藥理學(xué)方法初步探討十九畏中人參、五靈脂配伍對(duì)人參補(bǔ)氣作用的影響。方法:以人參單煎液、五靈脂單煎液及人參、五靈脂不同比例配伍混煎液(1∶1、1∶2、2∶1)灌胃給藥7天后,觀察小鼠游泳時(shí)間、耐寒、耐缺氧時(shí)間,測(cè)定胸腺指數(shù)、脾指數(shù)及肝糖元含量。結(jié)果:配伍組對(duì)正常小鼠游泳時(shí)間、耐寒、耐缺氧時(shí)間及胸腺指數(shù)、肝糖元含量均有增強(qiáng)作用(P<0.05),且以人參、五靈脂2∶1配伍組尤為明顯,與人參組比較有統(tǒng)計(jì)學(xué)差異(P<0.05)。結(jié)論:研究結(jié)果表明,人參與五靈脂配伍對(duì)
2、人參補(bǔ)氣作用的影響表現(xiàn)為相使配伍,這與傳統(tǒng)的理論認(rèn)識(shí)具有明顯不同,需要更多的理論和實(shí)驗(yàn)支撐?！ ￡P(guān)鍵詞:本文來(lái)自：www.luotuo.net.cn駱駝?wù)撐娜藚?五靈脂;配伍;補(bǔ)氣? TheRudimentPharmacodynamicsStudyontheEffectsof CompatibilityBetweenGinsengandTrogopterusDungoninvigoratingqiofGinseng LIANGAi?ling1,GAOMing?jian2,LILian?jun3,CHENShao
3、?hong4,ZHONGGan?sheng4 (1.BeijingRoyalIntegrativeMedicineHospital,Beijing102209,China; 2.Realisticpress,Beijing100165,China; 3.ZhuozhouHospitalofChineseMedicineinHebeiProvince,Zhuozhou070750,Hebei,China; 4.BeijingUniversityofChineseMedicine,Beijing100029,Chin
4、a) Abstract:Objective:PreliminarystudyontheeffectsofCompatibilitybetweenGinsengandTrogopterusDungoninvigoratingqiofGinsengbymeansofmodernpharmacologicaltechnique.Methods:HealthyICRmiceweretreatedbyintragastricadministrationrespectivelyusingGinseng,Trogopterusdun
5、g,Ginsengandfafcestrogopteroriintheratioof1∶1,1∶2,2∶1,andcompoundsalviatablets.After7days,swimmingtime,Coldresistanttime,hypoxiatolerancetimewereobserved;thymusglandindex,spleenindexandhepaticglycogencontentweremeasured.Results:Compatibilitygroupscouldincreaseswi
6、mmingtime,Coldresistanttime,hypoxiatolerancetime,thymusglandindexandhepaticglycogencontentinhealthymice(P<0.05),butGinsengandfafcestrogopteroriintheratioof2∶1inparticularhadsignificantdifference,comparedwithGinsenggroup(P<0.05).Conclusion:Theresultsindicatethatth
7、erelationofCompatibilitybetweenGinsengandTrogopterusdungismutualassistance,thisviewisdifferentfromtraditionaltheory,andstillneedsmoretheoryandexperiments.? Keywords:Ginseng;Trogopterusdung;compatibility;invigoratingqi 十八反、十九畏,自金元時(shí)期開始一直沿用至今,是眾所周知的中藥配伍禁忌,但古今文
8、獻(xiàn)又不乏破禁的藥對(duì)配伍或復(fù)方記載。因此有現(xiàn)代學(xué)者對(duì)傳統(tǒng)醫(yī)藥的這種配伍禁忌提出質(zhì)疑,并采用現(xiàn)代技術(shù)手段,通過(guò)藥理、毒理、藥化等方面的研究以期探討其配伍禁忌的實(shí)質(zhì)。人參、五靈脂作為十九畏中的一組藥對(duì),臨床上兩藥合用者亦不鮮見(jiàn),但缺乏充足的實(shí)驗(yàn)支持,為進(jìn)一步明確其是否屬配伍禁忌,探討其配伍實(shí)質(zhì),本實(shí)驗(yàn)通過(guò)應(yīng)激、免疫、物質(zhì)代
