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《奧沙拉嗪鈉加復(fù)方黃柏液涂劑保留灌腸治療慢性結(jié)腸炎的療效觀察》由會員上傳分享,免費在線閱讀,更多相關(guān)內(nèi)容在行業(yè)資料-天天文庫。
1、中國肛腸病雜志2008.10(4)奧沙拉嗪鈉加復(fù)方黃柏液涂劑保留灌腸治療慢性結(jié)腸炎的療效觀察浙江省紹興第二醫(yī)院(浙江紹興312000)艾衛(wèi)民浙江省嵊州市剡湖街道中心衛(wèi)生院(浙江嵊州312400)黃培余摘要[目的]以奧沙拉嗪鈉口服,復(fù)方黃柏液涂劑保留灌腸,以及奧沙拉嗪鈉加復(fù)方黃柏液涂劑保留灌腸各一組。觀察治療慢性結(jié)腸炎的療效及復(fù)發(fā)率.。[方法]采用隨機,雙盲對照設(shè)計進行臨床試驗。奧沙拉嗪鈉組27例,500㎎/次,3次/d,口服;復(fù)方黃柏液涂劑組29例,每晚1次,每次100ml,保留灌腸;復(fù)合組30例,用奧沙拉嗪鈉口服和復(fù)方黃柏液涂劑保留灌腸同時進行,劑量和方法同前兩組,三組療程均
2、為30天。[結(jié)果]奧沙拉嗪鈉組27例;30天后顯效13例,有效8例,無效6例,總有效率77.8%,復(fù)發(fā)7例(25.9%);復(fù)方黃柏液涂劑組29例;30天后顯效9例,有效13例,無效7例,總有效率77.86%,復(fù)發(fā)12例(41.3%);復(fù)合組30例:30天后顯效21例,有效8例,無效1例,總有效率96.67%,復(fù)發(fā)1例(3.33%)。經(jīng)統(tǒng)計學(xué)處理,三組間交叉對比分別為×2=0.014、×2=3.92、×2=4.68。前兩組間總有效率無統(tǒng)計學(xué)意義(P>0.05),?奧沙拉嗪鈉組和復(fù)方黃柏液涂劑組與復(fù)合組間總有效率差異顯著(P<0.05),療效顯著。關(guān)鍵詞;慢性結(jié)腸炎,奧沙拉嗪鈉、復(fù)
3、方黃柏液涂劑、保留灌腸ClinicalstudyontheeffectofRetentionEnemawitholsalazinesodiumandFufanghuangbailiquidinthetreatmentofchroniccolitisAiweiming,HuangpeiyuShaoxingsecondHospital,shaoxing,zhejiang312000shanhucomercenteralHospital,shengzhou,zhejiang312400Adstract[Objective]therearethreegroupsofcaseswithc
4、hroniccolitisandtreatedwiththeolsalazinesodium,theFufanghuangbailiquidandtheolsalazinesodiumcombinedwithfufanghuangbailiquidrespectively,observetheefficacyandrecurrencerateinthetreatmentofthecases.[Methods]wedesignedarandomized,doubleblindandcontrolstudy.The27patientsinthefirstgrouptookolsal
5、azinesodium500mgthreetimesdaily.The29patientsinthesecondweregivenanenemawithfufanghuangbailiquid100MLonceeverynight.The30patientsinthecomboudedgroup,Receivedthetwotherapymethods.thesametimeandwiththesamedosesandmethods.Thetreamentlastedfor30daysintheallthreegroups.[Results]After30days.amongt
6、hegroupwitholsalazinesodiumonly,13casesweredistictulitily,8caseswereefficiency,6caseswereineffiency.Thetotaleffectiveratewas77.8%,7casesrecurred(25.9%),amongthegroupwithfufanghuangbailiquidonly,9casesweredistictulitily,13caseswereefficiency,7caseswereineffiency.Thetotaleffectiveratewas77.86%
7、.12casesrecurred(41.3%),amongthebondedgroup,21casesweredistictulitily,8caseswereefficiency,1casewasineffiency.Thetotaleffectiveratewas96.67%,1caserecurred(3.33%).Processedbystatistics,thethreegroupsofdataeswerecontrastedtwo-twotheresultswere×2=0.01