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1、孟魯司特鈉治療108例兒童咳嗽變異性哮喘療效分析姚彬彬莊洪濤邱琦(海寧市婦幼保健院兒科314400)【摘要】目的探究與分析孟魯司特鈉治療108例兒童咳嗽變異性哮喘的臨床療效。方法選取我院呼吸內(nèi)科收治的兒童咳嗽變異型哮喘216例并將其作為研究對(duì)象(經(jīng)木人及家長(zhǎng)同意),按照患者意愿分為甲,乙兩組,每組均為108名患者。甲組為實(shí)驗(yàn)組,我院采用孟魯司特鈉口服給藥的治療方案;乙組為對(duì)照組,釆用抗炎平喘藥糖皮質(zhì)激素布地奈德的治療方案。通過一段時(shí)間的治療,觀察并分析兩組患者經(jīng)不同的治療方案治療后的臨床療效。結(jié)果甲乙兩組患者經(jīng)過不同的治療方案治療后,甲組患者的治療有效人數(shù)較乙組高,并且哮
2、喘次數(shù),氣短,出汗,焦慮以及咳嗽等癥狀顯著減少,P<0.05,具有統(tǒng)計(jì)學(xué)意義。結(jié)論在兒童咳嗽變異性哮喘的治療過程中,孟獸司特鈉的治療方案比較傳統(tǒng)呼吸內(nèi)科使用糖皮質(zhì)激素的治療方案療效更佳顯著,副作用明顯減少,因此在臨床上具有一定的指導(dǎo)意義?!娟P(guān)鍵詞】?jī)和人宰儺愋拖萧斔咎剽c療效分析【中圖分類號(hào)】R720.5【文獻(xiàn)標(biāo)識(shí)碼】A【文章編號(hào)】2095-1752(2012)35-0177-02Analysecurativeeffectofusingmontelukastsodiumtotreat108casesofchildrencoughvariantasthma[Abs
3、tract]objectives:Todiscussandnanalyseclinicalcurativeeffectofusingmontelukastsodiumtotreat108casesofchildrencoughvariantasthma.Methods:Chose216casesofthosechildrencoughvariantasthmapatientswhohavebeenadmittedatrespiratorymedicinedepartmentofourhospitalasstudyobjectives(permittedbythemselv
4、esandtheirparents),dividedthemintothefirstandthesecondgroupaccordingtotheirwillingness,eachgrouphas108casesofpatients.Thefirstgroupwasexperimentalgroup,gaveoraladministrationofmontelukastsodiumastreatmenttothem;Thesecondgroupwascontrolgroup,adoptedanti-inflammatoryantiasthmaticglucocortic
5、oidbudesonideastreatmenttothem.Observedandanalysedthesetwogroups’patients’clinicalcuratiiveeffectsaftertheyhavebeentreatedbydifferentmethodsforaperiodoftime.Results:Aftertreatedbydifferentmethods,thetreatmenteffectivenumberinthefirstgroupwasmorethanthesecondgroup’s,andth
6、eirsymptomsofasthmafrequencies,breathehard,perspire,anxietyandcoughweredecreasedsignificantly,p<0.05,ithasstatisticsmeaning.Conclusions:Withregardtotreatmentforchildrencoughvariantasthma,montelukastsodium’sclinicalcurativeeffectwasbetterthanglucocorticoid’s,anditssideeffect
7、sdiminishedsignificantly,therefore,ithassomedegreeofguidingvalueinclinical.【KeyWords]childrencoughvariantasthmamontelukastsodiumanalysisofcurativeeffect兒童咳嗽變異型哮喘的發(fā)病的本質(zhì)為變態(tài)反應(yīng),是一種特殊類型的兒童支氣管哮喘,由患兒長(zhǎng)期咳嗽變異而來,長(zhǎng)期不治愈可引起兒童慢性咳嗽等一系列呼吸系統(tǒng)疾病,也可能危及生命?,F(xiàn)在臨床上治療哮喘的方法主要是糖皮質(zhì)激素UI服給藥,但由于激素的