消癌平注射液聯(lián)合放化療在局部中晚期鼻咽癌治療中的療效觀察

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1、消癌平注射液聯(lián)合放化療在局部中晚期鼻咽癌治療中的療效觀察【摘要】日的：觀察消癌平注射液聯(lián)合誘導(dǎo)化療及同步放化療在局部中晩期鼻咽癌治療中的療效觀察。方法：選収局部中晩期鼻咽癌患者60例，按隨機(jī)數(shù)字表法分為治療組（消癌平組聯(lián)合放化療組）30例和對照組（單純放化療組）30例，兩組治療前均未行過化療、放療、免疫治療及中醫(yī)屮藥治療等。觀察治療結(jié)束后兩組腫瘤病灶變化情況、皮膚及口腔黏膜反應(yīng)、骨髓抑制程度和肝腎功能情況。結(jié)果：治療結(jié)束12個月后復(fù)查，治療組完全緩解率高于對照組，差異有統(tǒng)計學(xué)意義（P〈0?05）；且

2、骨髓抑制較對照組輕（P〈0?05）,其他毒副評價相當(dāng)。結(jié)論：消癌平注射液聯(lián)合放化療治療中晚期鼻咽癌具有增效、減毒作用，值得進(jìn)一步研究證實?！娟P(guān)鍵詞】消癌平注射液；鼻咽癌；誘導(dǎo)化療；同步放化療ClinicalObservationofXiaoaipingCombinedwithRadiationandChemotherapyinTreatmentofNasopharyngealCarcinoma（NPC）/XIAOHong-mei,ZOUYan,WUXiao~liang.//MedicalInnova

3、tionofChina,2014,11（28）：051-053[Abstract】Objective：ToobservetheoutcomeofcombiningXiaoaipinginjectiontreatmentwithinducingchemotherapyandconcurrentchemoradiotherapyonlocallyadvancednasopharyngeedcancer?Method：60patientswithnasopharyngealcarcinoma(NPC)we

4、reselect,thepatientswererandomlydividedintotwogroups：onegroupof30patientsweretreatedwithXiaoaipingcombinedwithinducingchemotherapyandconcurrentchemoradiotherapy(thetreatmentgroup),andtheothergroupof30patientswastreatedsolelywithinducingchemotherapyandc

5、oncurrentchemoradiotherapy(thecontrolgroup)?Thetwogroupsbeforetreatmenthadnotbeendonechemotherapy,radiationtherapy,immunotherapyandChinesemedicinetroatmont,etc.Thechangosofthetumoraftertreatment,thereactionofskinandmucousmembraneofmouth,bonemarrowinhib

6、itiondegree,liverandkidneyfunctionwereobserved?Result：Checkedover12monthsaftertreatment,completeresponserateofthetreatmentgroupwashigherthanthecontrolgroup,thedifferencewasstatisticallysignificant(P<0.05),bonemarrowsuppressionwas1ighterthanthecontrolgr

7、oup(P<0.05),theothersideevaluationwerefairly.Conclusion：Xiaoaipingunitesradiationandchemotherapycanincreasethecurativeeffectoflocallyadvancednasopharyngealcarcinoma,toreducetheadversereaction.【Keywords]Xiaoaipinginjection；Nasopharyngealcarcinoma；Tnduct

8、ionchemotherapy；ChemoradiationFirst-authorsaddress：ZunyiMedicalCollegeAffiliatedTumorHospital,Zunyi563000,Chinadoi：10.3969/j.issrt1674-4985.2014.28.018鼻咽癌是頭頸部常見的惡性腫瘤之一，放射治療是其主要治療方法。但因鼻咽癌癥狀缺乏典型性容易與其他良性病變混淆，故很多患者確診時已屬局部晚期，這類患者大多數(shù)需行誘導(dǎo)化療聯(lián)合同