懷山藥炮制工藝與質量標準-.研究

懷山藥炮制工藝與質量標準-.研究

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時間:2019-01-29

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1、英文摘要TheStudyonPreparationTechnologyandQualityStandardofDioscoreaeRhizomaDuShaoliang(Pharmacochemistry)DirectedbyYangYunandzhangzhenlingAbstractObjective:ThesubjectofthisresearchwasDioscoreaeRhizoma,Westudiedthehistoryandtheprimaryintentionoftheprocesssingandmodernresearchprogress,wh

2、ichprovidedthecluesandbasisforthissubject.Onthebasiswestudiedtheprocessing、thequalitystandardsandthefingerprintofDioscoreaeRhizoma.toprovidingexperimentaldataforthestandardizedprocessing,therebyimproveandensurethequalityofDioscoreaeRhizoma,ensuretheclinicalmedicationeffectiveandsafe

3、.Methods:(1)ApplyingthemoderninstrumenttestingtechnologytoinvestigatetheeffectsofdifferentprocessingmethodsonthechemicalcompositioninDioscoreaeRhizoma,Inthemeantime,stableandreliablecontentdeterminationmethodofallantoin﹑diosgeninandpolysaccharideshasbeenestablishedbyHPLCandUV;(2)Sys

4、tematicalstudyontheprocessingtechnologyofDioscoreaeRhizomahasbeenperformedinthistask.Firstly,researchthebestprocessingmethodofDioscoreaeRhizomasofteningandcutting,theoptimumtechnologyconditionswere4selectedbyL9(3)orthogonaldesignonthebaseofthesinglefactorinvestigation,orthogonaltest

5、aredecidedwithfoureffects:immersiontime,moisteningtime,numberofaddingwateranddryingtemperature,accordingtothecontentofallantoin,polysaccharideandwater-solubleextractive,thetestresultswereanalyzedbycomprehensiveweightedscore;Andthenthereisprocessingofstir-fryingwithbranforDioscoreaeR

6、hizomabymulti-indexorthogonaldesign,onthebaseofthesinglefactorinvestigation,Theorthogonaldesignwasemployedtodeterminetheeffectsofthefourfactorsaffiliatedwiththreelevelsincludingtemperature,time,branamount,particalsizeofbranandthefourindexesofthecontentsofallantoin,polysaccharide,dio

7、sgenin,togetherwithshapeandappearance;(3)StudyonqualitystandardsforDioscoreaeRhizoma,Thequalitystandard10batchesofDioscoreaeRhizomawasconstitutedthroughqualitative-quantitativeanalysisandmicroscopicidentification.3懷山藥炮制工藝及質量標準研究Meanwhile,determinemoisturecontent、ash-content,water-so

8、lubleextractivecont

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