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1、分類號學號D200978368學校代碼10487密級博士學位論文VRACs阻斷劑對小膠質(zhì)細胞生長和活化的調(diào)控及機制研究學位申請人:李正偉學科專業(yè):外科學(神經(jīng)外科)指導(dǎo)教師:陳勁草教授答辯日期:2012.5.11AdissertationsubmittedtoHuazhongUniversityofScienceandTechnologyfortheDegreeofDoctorofNeurosurgeryEffectsofVRACsinhibitoronmicrogliagrowthandactivation
2、,andmechanismsunderlyingsucheffectsD.Candidate:LiZhengweiMajor:NeurosurgerySupervisor:Prof.ChenJincaoHuazhongUniversityofScience&TechnologyWuhan430074,P.R.ChinaMay,2012獨創(chuàng)性聲明本人鄭重聲明,本學位論文是本人在導(dǎo)師指導(dǎo)下進行的研究工作及取得的研究成果的總結(jié)。盡我所知,除文中已經(jīng)標明引用的內(nèi)容外,本論文不包含任何其他個人或集體已經(jīng)發(fā)表或撰寫過的研
3、究成果。對本文的研究做出貢獻的個人和集體,均已在文中以明確方式標明。本人完全意識到本人將承擔本聲明引起的一切法律后果。學位論文作者簽名:日期:年月日學位論文版權(quán)使用授權(quán)書本學位論文作者完全了解學校有關(guān)保留、使用學位論文的規(guī)定,即:學校有權(quán)保留并向國家有關(guān)部門或機構(gòu)送交論文的復(fù)印件和電子版,允許論文被查閱和借閱。本人授權(quán)華中科技大學可以將本學位論文的全部或部分內(nèi)容編入有關(guān)數(shù)據(jù)庫進行檢索,可以采用影印、縮印或掃描等復(fù)制手段保存和匯編本學位論文。保密□,在_____年解密后適用本授權(quán)書。本論文屬于不保密□。(請在以
4、上方框內(nèi)打“√”)學位論文作者簽名:指導(dǎo)教師簽名:日期:年月日日期:年月日華中科技大學博士學位論文目錄主要縮略詞表···························································································1中文摘要·································································································2Abstra
5、ct··································································································5前言····································································································8第一部分VRACs阻斷劑對小膠質(zhì)細胞增殖的調(diào)控及機制研究·························
6、·12材料與方法··························································································13結(jié)果································································································24討論·······················································
7、·········································25參考文獻·····························································································27附圖································································································30第二部分VRACs阻斷劑對小膠
8、質(zhì)細胞凋亡的調(diào)控及機制研究··························35材料與方法··························································································36結(jié)果·····························································