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1、萬方數(shù)據(jù)天津醫(yī)科大學(xué)碩士學(xué)位論文1.1H—MRSanalysisindicatesthattype-2diabetesmellitusmaycausesubtlechangesinthemetabolicprotileofthebrain.2.DecreasedconcentrationsofNAAandincreasedconcentrationsofChomightbeindicativeofdecreasedneuronalviabilityindiabetics.3.HbAlcwerene
2、gativelycorrelatedwithNAAintherightfrontalcortexofpatientsintheT2DM.Thesefindingssuggestedthatneuronaldamagewasmoreseriousinpatientswithdiabeteswithpoorglycemiccontrolthaninwell—controlledpatients.Keywords:protonmagneticresonancespectroscopyrype2diabe
3、tesCognitionMetabolitesFrontallobeV萬方數(shù)據(jù)天津醫(yī)科大學(xué)碩士學(xué)位論文目錄中文摘要?????????????????????????????TAbstract?????????????????????????????ⅡI縮略語?????????????????????????????Ⅵ前言???????????????????????????????1研究背景、現(xiàn)狀?????????????????????????1研究目的、方法??????????????????
4、???????3對象和方法??????????????????????????4結(jié)果?????????????????????????????10討論?????????????????????????????13結(jié)論???????????????????????????????20參考文獻(xiàn)?????????????????????????????21發(fā)表論文和參加科研情況說明????????????????????27綜述???????????????????????????????28綜述參考文
5、獻(xiàn)??????????????????????????39致謝???????????????????????????????46V萬方數(shù)據(jù)天津醫(yī)科大學(xué)碩士學(xué)位論文ADAlaAspABCrChoETHFBGGlxGluGlnGlvGABAGLTH1HMRSHDLHbAlCIRLacLDLLipMIMMSENAANFTPCPETHSAS縮略語/符說明Alzheimer’Sdiseasealanineaspartatep-amyloidproteincreatine/phosphocreatinecho
6、line-containingcompoundsethanolamin.eFastingboold—glucosegluamate+glutamine+Y-hydroxybutyricacidcomplexglutamateGlutamineglycineY—hydroxybuty’ricacidglutathioneprotonmagneticresonancespectroscopyhighdensitylipoproteinGlycatedhemoglobinInsulinrceptorla
7、ctatelowdensitylipoproteinlipidmyo-inositolmini.mentalstateexaminationN—acetylaspartateneurofibrillarytanglesphosphorylcholinephosphorylethanolamineSelf-RatingAnxietyScale阿爾茨海默病丙氨酸天冬氨酸淀粉樣蛋白肌酸/磷酸肌酸膽堿化合物乙醇胺空腹血糖谷氨酸鹽一谷氨酰胺吖羥基丁酸復(fù)合物谷氨酸鹽谷氨酰胺甘氨酸Y一氨基丁酸谷胱甘肽氫質(zhì)子磁共
8、振波譜糖化血紅蛋白胰島素受體乳酸脂質(zhì)肌醇簡易精神狀態(tài)檢查N一乙酰天門冬氨酸神經(jīng)纖維纏結(jié)磷酸膽堿磷酸乙醇胺焦慮自評量表萬方數(shù)據(jù)天津醫(yī)科大學(xué)碩士學(xué)位論文SDSSISTEAMTCTGTETauT2DMVOISelf-RatingDepressionScalescyllo-inositolstimulatedechoacquisitionmodetotalcholesteroltriglycerideechotimetaurineType2diabetesmellitusvoxelofin