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1、維普資訊http://www.cqvip.com2003年4月第41卷第4期ChinJSurg,April2003,Vol_4.·27l·.臨床論著侵及鄰近結構的胃底賁門癌手術方式的探討蘭邵平張祥福盧輝山吳心愿黃昌明官國先王川【摘要】目的探討腫瘤侵及鄰近結構(tumorinvadesadjacentstructures,T4)的胃底賁門癌外科治療的最佳方式。方法對201例T4胃底賁門癌進行外科治療,其中探查手術31例,聯(lián)合臟器切除術170例。對聯(lián)合臟器切除術后3、5年生存率及術后病死率和并發(fā)癥發(fā)生率進行分析。結果探查手術和聯(lián)合臟器切除術
2、患者的中位生存期分別為4.9個月和29.3個月,二者間差異有非常顯著性意義(=37.080,P<0.o1)。170例施行聯(lián)合臟器切除術患者的3、5年生存率分別為46.2%、22.8%;其中全胃切除術患者的3、5年生存率分別為54.9%、29.2%,明顯高于近側(cè)胃大部切除術患者的32.2%、12.5%()(2=7.589、P<0.o1,)(2=5.792、P<0.05)。術后病死率和并發(fā)癥發(fā)生率分別為4.1%和24.1%。結論對于T4胃底賁門癌患者,只要術中沒有發(fā)現(xiàn)肝臟血行轉(zhuǎn)移、淋巴結廣泛轉(zhuǎn)移和腹膜種植轉(zhuǎn)移等,局部病變允許行聯(lián)合臟器整塊切
3、除,且患者的身體狀況許可,就應盡可能施行聯(lián)合臟器切除術,以達到根治的目的。全胃切除術能夠提高療效?!娟P鍵詞】胃腫瘤;}肖化系統(tǒng)外科手術;預后Therapeuticefectsofoperationintul~orinvadesadjacentstructurescan~erofcardiaandstomachfundusL4ⅣShao-ping,ZHANGXiang-fu,LHui—shan,WUXin—yl,~n,HUANGChang—ming.GUANGuo—xian,WANGChuan.DepartmentofOncology,A
4、ffiliatedUnionHospital。FujianMedicalUniversity,F(xiàn)uzhou35O001.China【Abstract】0bjectiveTostudythebeststyleofoperationinthetreatmentoftumorinvadesadjacentstructures(T4)canceroftl1ecardiaandstomachfundus.MethodsTwohundredandonepatientswithT4canceroftl1ecardiaandstomachfundusu
5、nderwentoperation.Ofthem,31weretreatedbylaparotomy.a(chǎn)nd170bycombinedresectionoftheinvolredorgans.The3一and5-yearsurvivalratesandtl1epostoperativecomplicationrateandmortalityratewereanalyzedinthepatientswhohadundergonecombinedresectionoftl1einvolvedorgans.ResultsThemediansu
6、rvivalofthepatientsundergoingcombinedresectionoftheinvolvedorgans(29.3months)wassignificantlylongerthanthatofthosereceivinglaparotomy(4.9mOBtl1S).The3-and5-yearsurvivalratesof170patientswhohadundergonecombinedresectionoftl1einvolvedorganswere46.2%and22.8%.respectively.Th
7、e3一and5-yearsurvivalratesofpatientsundergoingtotalgastrectomyandproximalgastrectomywere54.9%and29.2%and32.2%and12.5%,respectively,andthediferencewasstatisticallysignificant(×=7.589,P<0.O1;x=5.792,P<0.05).rI1hepostoperativemortalityrateandcomplicationratewere4.1%and24.1%.
8、respectively.ConclusionsrI'}Ipatientswithoutlivermetastasis,widespreadnodalinvolvement.peritone~dissemi