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《鉤吻素子抗神經(jīng)病理性疼痛作用與脊髓神經(jīng)活性甾體別孕烯醇酮的關(guān)系》由會員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在學(xué)術(shù)論文-天天文庫。
1、分類號：R96學(xué)校代碼：10392學(xué)科專業(yè)代碼：100706學(xué)號：200902057福建醫(yī)科大學(xué)博士研究生畢業(yè)論文鉤吻素子抗神經(jīng)病理性疼痛作用與脊髓神經(jīng)活性甾體別孕烯醇酮的關(guān)系A(chǔ)ntagonisticeffectsofkoumineonneuropathicpainanditsrelationshipwiththeneurosteroidallopregnenoloneinspinalcord學(xué)位類型：醫(yī)學(xué)博士所在學(xué)院：藥學(xué)院研究生：丘宏強(qiáng)學(xué)科、專業(yè)：藥理學(xué)導(dǎo)師：俞昌喜教授研究起止日期：二○○九年九
2、月至二○一三年二月答辯日期：二○一三年六月一日二○一三年六月鉤吻素子抗神經(jīng)病理性疼痛作用與脊髓神經(jīng)活性甾體別孕烯醇酮的關(guān)系目錄英文縮寫字表..................................................................................1一、中文摘要............................................................................................3二
3、、英文摘要............................................................................................8三、前言..................................................................................................13四、材料與方法...........................................
4、...........................................16五、結(jié)果..................................................................................................34六、討論..................................................................................................5
5、2七、結(jié)論..................................................................................................61八、參考文獻(xiàn)..........................................................................................62九、綜述.............................................
6、.....................................................68附錄…………………………………………………………………..82致謝…………………………………………………………………..83鉤吻素子抗神經(jīng)病理性疼痛作用與脊髓神經(jīng)活性甾體別孕烯醇酮的關(guān)系英文縮寫字表英文縮寫英文全稱中文名稱NPPNeuropathicPain神經(jīng)病理性疼痛InternationalAssociationfortheStudyofIASP國際疼痛研究協(xié)會PainKMKoumin
7、e鉤吻素子GMGelsemine鉤吻素甲ApAllopregnenolone別孕烯醇酮3α,5α-THP3α,5α-tetrahydroprogesterone3α,5α-四氫孕酮3α-HSD3α-hydroxysteroidoxido-reductase3α-羥化固醇氧化還原酶PregPregnenolone孕烯醇酮5α-DHP5α-Dihydroprogesterone5α-二氫孕酮2NFPH2-Nitro-4-(trifluoromethyl)phenylhydrazine2-硝基-4-三氟甲
8、基苯肼CCIChronicconstrictioninjury慢性結(jié)扎損傷CNSCentralnervoussystem中樞神經(jīng)系統(tǒng)DHDorsalhorn背角ED50Effectivedose50%半數(shù)有效量LD50Lethaldose50%半數(shù)致死量MWTMechenicalWithdrawalThreshold機(jī)械刺激痛閾TWLThermalWithdrawalLatency熱輻射痛閾1鉤吻素子抗神經(jīng)病理性疼痛作用與脊髓神經(jīng)活性甾體別孕烯醇酮的關(guān)系NeuNNeu
