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1、授予單位代碼10089學(xué)號(hào)或申請(qǐng)?zhí)?3004V妗(￡搿大空HebeiMedicalUniversity碩士學(xué)位論文在職科學(xué)學(xué)位冠狀動(dòng)脈病變程度與左室舒張功能的相關(guān)性研究學(xué)位申請(qǐng)人：李春彥導(dǎo)師：齊曉勇教授專業(yè)：內(nèi)科學(xué)二級(jí)學(xué)院：河北省人民醫(yī)院2015年3月河北醫(yī)科大學(xué)學(xué)位論文使用授權(quán)及知識(shí)產(chǎn)權(quán)歸屬承諾本學(xué)位論文在導(dǎo)師(或指導(dǎo)小組)的指導(dǎo)下，由本人獨(dú)立完成。本學(xué)位論文研究所獲得的研究成果，其知識(shí)產(chǎn)權(quán)歸河北醫(yī)科大學(xué)所有。河北醫(yī)科大學(xué)有權(quán)對(duì)本學(xué)位論文進(jìn)行交流、公開和使用。凡發(fā)表與學(xué)位論文主要內(nèi)容相關(guān)的論文,第一署名為單位河北醫(yī)科大學(xué)，試驗(yàn)材料、原始數(shù)據(jù)、申報(bào)的專利等知識(shí)產(chǎn)權(quán)均歸河北醫(yī)科
2、大學(xué)所有。否則，承擔(dān)相應(yīng)法律責(zé)任。/'樣人>二級(jí)學(xué)院領(lǐng)導(dǎo)毒筆夢(mèng)\rtm#/河北醫(yī)科大學(xué)研究生學(xué)位論文獨(dú)創(chuàng)性聲明本論文是在導(dǎo)師指導(dǎo)下進(jìn)行的研究工作及取得的研究成果,除了文中特別加以標(biāo)注和致謝等內(nèi)容外,文中不包含其他人已經(jīng)發(fā)表或撰寫的研究成果,指導(dǎo)教師對(duì)此進(jìn)行了審定。本論文由本人獨(dú)立撰寫,文責(zé)自負(fù)。研究生簽名：導(dǎo)師簽章:yny年J"月》1曰目錄中文摘要·············································································1英文摘要·································
3、············································3研究論文冠狀動(dòng)脈病變程度與左室舒張功能的相關(guān)性研究前言·············································································6材料與方法····································································7結(jié)果··································································
4、···········9附圖·············································································10附表·············································································11討論·············································································14結(jié)論···································
5、··········································16參考文獻(xiàn)·······································································16綜述左心舒張功能不全及其檢測(cè)方法······································21致謝···················································································28個(gè)人簡(jiǎn)歷························
6、·····················································29中文摘要冠狀動(dòng)脈病變程度與左室舒張功能的相關(guān)性研究摘要背景：我們?cè)谂R床工作中發(fā)現(xiàn)許多年輕冠心病患者超聲心動(dòng)圖E/Ea比值較大，提示舒張功能不全，但患者無明顯高血壓、心肌肥厚等引起左室舒張功能不全的因素，甚至糖尿病時(shí)間并不長(zhǎng)，而冠脈造影提示有明顯的冠脈狹窄性病變，考慮其心功能不全與冠脈病變有一定關(guān)系，故收集符合入選標(biāo)準(zhǔn)的均行冠脈造影檢查及超聲心動(dòng)圖檢查的患者資料139例，進(jìn)行冠心病冠脈病變程度與左室舒張功能的相關(guān)性分析，觀察其關(guān)系，從而對(duì)評(píng)估患者預(yù)后及指導(dǎo)進(jìn)一步治療提供幫
7、助。目的：本研究通過設(shè)定患者冠脈病變程度、血糖、總膽固醇、甘油三脂、高密度膽固醇、低密度膽固醇、同型半胱氨酸為自變量，患者超聲心動(dòng)圖E/A比值、E’值、EE’比值這些心臟舒張功能相關(guān)的指標(biāo)為應(yīng)變量，多元線性回歸分析觀察冠狀動(dòng)脈病變程度等與左室舒張功能之間的關(guān)系，探討其臨床意義。因糖尿病、年齡、同型半胱氨酸、血脂等因素均對(duì)舒張功能存在影響，同時(shí)觀察了這些指標(biāo)與左室舒張功能及冠脈病變的關(guān)系，對(duì)主要研究目的有一定排除意義。方法：回顧2014年4月～2015年2月在我院（河北北方學(xué)院附屬第二醫(yī)院）
