自噬在雌激素缺乏骨質(zhì)疏松小鼠骨髓間充質(zhì)干細(xì)胞分化平衡中的作用研究

自噬在雌激素缺乏骨質(zhì)疏松小鼠骨髓間充質(zhì)干細(xì)胞分化平衡中的作用研究

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自噬在雌激素缺乏骨質(zhì)疏松小鼠骨髓間充質(zhì)干細(xì)胞分化平衡中的作用研究_第1頁
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1、分類號(hào)R780.2第四軍醫(yī)大學(xué)UDC616.7TheFourthMilitaryMedicalUniversity密級(jí)公開碩士學(xué)位論文自噬在雌激素缺乏骨質(zhì)疏松小鼠骨髓間充質(zhì)干細(xì)胞分化平衡中的作用研究戚朦培養(yǎng)類別全日制學(xué)位類型學(xué)術(shù)學(xué)位一級(jí)學(xué)科(專業(yè)類)口腔醫(yī)學(xué)二級(jí)學(xué)科(專業(yè))口腔基礎(chǔ)醫(yī)學(xué)研究方向干細(xì)胞與調(diào)控指導(dǎo)教師金巖教授(主任醫(yī)師)培養(yǎng)單位口腔醫(yī)院組織病理科二O一五年五月第四軍醫(yī)大學(xué)碩士學(xué)位論文目錄縮略語表·················································

2、·············································1中文摘要······························································································2英文摘要······························································································7前言········

3、·····················································································13文獻(xiàn)回顧·····························································································14正文··································································

4、···························22第一部分雌激素缺乏性骨質(zhì)疏松小鼠骨髓充質(zhì)干細(xì)胞自噬水平的變化··········221實(shí)驗(yàn)材料·····················································································222實(shí)驗(yàn)方法·····················································································2

5、43實(shí)驗(yàn)結(jié)果·····················································································314討論···························································································31第二部分體外調(diào)節(jié)小鼠骨髓間充質(zhì)干細(xì)胞自噬水平對(duì)其分化功能的影響·······331實(shí)驗(yàn)材料····················

6、·································································332實(shí)驗(yàn)方法·····················································································343實(shí)驗(yàn)結(jié)果·····················································································374討論

7、···························································································39第三部分調(diào)節(jié)小鼠體內(nèi)自噬水平對(duì)骨量及骨髓間充質(zhì)干細(xì)胞分化功能影響····411實(shí)驗(yàn)材料·····················································································412實(shí)驗(yàn)方法··························

8、···························································413實(shí)驗(yàn)結(jié)果·····················································································454討論··································································

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