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1、舒利迭治療COPD緩解期34例療效觀察［摘要］目的探討舒利迭治療慢性阻塞性肺疾?。–OPD）緩解期的臨床療效。方法將68例住院COPD緩解期患者隨機分為治療組和對照組。對照組患者予以COPD常規(guī)治療，包括低流量持續(xù)吸氧，預防感染，常規(guī)服用氨茶堿，增強機體免疫力，吸入異丙托漠鍍,呼吸肌鍛煉及按需使用沙丁胺醇。治療組在對照組治療的基礎上加用舒利迭粉吸入劑，1吸/次,1次/d,每次2噴。兩組患者療程均為3個月。結(jié)果治療組總有效率為88.24%,對照組總有效率為67.65%,兩組總有效率比較差異有統(tǒng)計學意義（P<0.05）b治療后治療組患者的用力肺活量（FVC,第一秒用力呼氣容積（FEV
2、1）及FEV1/FVC均明顯優(yōu)于對照組，差異有統(tǒng)計學意義（P<0.05）;治療后治療組患者的動脈血氧分壓（PaO2X二氧化碳分壓（PaCO2）均明顯優(yōu)于對照組,差異有統(tǒng)計學意義（P<0.05）b結(jié)論舒利迭吸入是COPD緩解期患者的一種有效、安全的治療方法。［關(guān)鍵詞］慢性阻塞性肺疾?。皇胬?；肺功能［中圖分類號］R563.1［文獻標識碼］A［文章編號］1673-7210(2012)01(c)-0079-03ObservationofcurativeeffectsonSeretideinthetreatmentof34patientswithchronicobstructivepul
3、monarydiseaseofremissionphaseWANGZhengweiWEILipingHEShengCAIYaoquanDepartmentofRespiration,theThirdAffiliatedHospitalofGuangzhouMedicalCollege,GuangdongProvinee,Guangzhou510150,China[Abstract]ObjectiveToinvestigatethecurativeeffectsofSeretideinthetreatmentofpatientswithchronicobstructivepulmo
4、narydisease(COPD)ofremissionphase.Methods68hospitalizedpatientsintheCOPDremissionphasewererandomlydividedintotreatmentgroupandcontrolgroup.ThecontrolgroupreceivedCOPDconventionaltreatment,includinguptakeoflow-flowcontinuousoxygen,preventionofinfection,routineadministrationofaminophylline,incr
5、easeofbodyimmunity,inhalationofipratropiumbromide,trainingofrespiratorymuscleandon-demanduseofsalbutamol.Thetreatmentgroupreceivedadditionalseretidepowderinhalant1inhalationeverytime,onceadayand2prayseverytimeonthebasisofconventionaltreatment.Thetreatmentcourseforbothgroupswas3months.ResultsT
6、hetotaleffectiveratewas88.24%inthetreatmentgroupandthetotaleffectiveratewas67.65%inthecontrolgroup,withstatisticallysignificantdifferencebetweenthetwogroups(P<0.05).Aftertreatment,thetreatmentgroupwassuperiortothecontrolgroupinforcedvitalcapacity(FVC),forcedexpiratoryvolumein1second(FEV1)andF
7、EV1/FVC,withstatisticallysignificantdifferences(P<0.05).Aftertreatment,thetreatmentgroupwassuperiortothecontrolgroupinPaO2andPaCO2,withstatisticallysignificantdifferences(P<0.05).ConclusionSeretideinhalationisasafeandeffectivetherapyforpatien
