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1、甘麥大棗湯聯合天王補心丹治療乳腺癌類圍絕經期綜合征的臨床效果觀察[摘要]目的觀察廿麥大棗湯聯合天王補心丹治療乳腺癌類I韋I絕經期綜合征的臨床效果。方法選擇本科收治的72例乳腺癌類圍絕經期綜合征患者,隨機分為甘麥大棗湯聯合天王補心丹治療組(觀察組)及內分泌基礎治療組(對照組),觀察兩組的癥狀積分、生活質量積分、E2及FSH水平,進行安全性評價。結果治療前,兩組的相關觀察指標比較差異無統(tǒng)計學意義(P>0.05);治療后,觀察組的癥狀積分、FSH水平低于對照組,生活質量積分、E2水平高于對照組,差異有統(tǒng)計學意義(PC0.05);兩組均未出現異常及不良反應。結論甘麥大棗湯聯合天王補心丹
2、治療乳腺癌類圍絕經期綜合征,可有效改善患者的癥狀及激素水平,且安全性較高。[關鍵詞]乳腺癌;類I韋I絕經期綜合征;中藥[中圖分類號]R737.9[文獻標識碼]A[文章編號]1674-4721(2014)09(c)-0070-03ClinicaleffectobservationofGanmaidazaodecoctioncombinedwithTianwangbuxindaninthetreatmentofmammarycancerclassperimenopausalsyndromeWUWen-zhongDepartmentofInternalMedicineIII,Peop
3、le'sHospitalofHengdongCountyinHunan卩rovince,Hengdong421400,China[Abstract]ObjectiveToobserveclinicaleffectofGanmaidazaodecoctioncombinedwithTianwangbuxindaninthetreatmentofmammarycancerclassperimenopausalsyndrome.Methods72casesofpatientswithmammarycancerclassperimenopausalsyndromeinourdepart
4、mentwereselectedandrandomlydividedintoGanmaidazaodecoctioncombinedwithTianwangbuxindantreatmentgroup(observationgroup)andendocrinebasicaltreatmentgroup(controlgroup)?Thesyndromescore,qualityoflifescore,E2andFSHlevelintwogroupswasobservedrespectively,andsafetyevaluationwasimplemented?ResultsB
5、eforetreatment,relatedindexintwogroupswascompared,withnostatisticaldifferenee(P>0.05)?Aftertreatment,syndromescore,FSHlevelinobservationgroupwaslowerthanthatincontrolgrouprespectively,qualityoflifescoreandE2levelinobservetiongroupwashigherthanthatincontrolgrouprespectively,withstatisticaldif
6、ference(P<0.05)?Patientsoftwogroupsdidn1toccurredabnormalityandadversereaction.ConclusionGanmaidazaodecoctioncombinedwithTianwangbuxindaninthetreatmentofmammarycancerclassperimenopausalsyndromecanobviouslyimprovepatients‘syndromeandhormonelevel,andhavehighersafety.[Keywords]Mammarj^cancer;Cl
7、assperimenopausalsyndrome;TraditionalChinesemedicine乳腺癌屬于最常見的婦科惡性腫瘤,是導致婦女死亡的主要原因之一,隨肴醫(yī)療技術的不斷進步,乳腺癌發(fā)病率呈不斷上升趨勢,內分泌治療以其可降低雌激素水平、改善內分泌環(huán)境、降低復發(fā)率而在乳腺癌治療中發(fā)揮越來越重要的作用,但長時間應用該治療措施可誘發(fā)如潮熱汗出、心悸失眠、腰膝酸軟、煩躁易怒、月經不調籌類圍絕經期綜合征癥狀[1-2],嚴重影響患者生活質量,口長期服藥易導致患者的依從性差而影響療效,故而探