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1、海峽藥學(xué)2010年第22卷第9期[29】M0dugrIoM．。caSaleE．。SonciniC．，eta1．Crystalstructureofthechromosome-sprindleattachmentsduringceldivision[J]．Nat．CelT3151AblmutantincompIlexwiththeaurorakinasesinhibitorBio1．，2004．6(3)：232．237．PHA-739358[J3．CancerRes．，2007．67(17)：7987．7990．
2、【363HaufS．，LohR．，LaTerraS．。eta1．ThesmallmoleculeHesperadin【3O】AnandS．。Penrhyn．1oweS．．VenkitaramanA．Aurora-Aamplifica．revealsaroleofAuroraBincorrectingkinetochore-microtubuleat．tionoverridesthemitoticspindleassemblycheckpoint，inducingre．tachmentandinmaintaini
3、ngthespindleassemblycheckpoint【J】sistancetoTaxol[J】．CancerCeU，2003，3(1)：51—62．．CeUBio1．2003。161(2)：281．294．[313MortlockA．．FooteK．．eta1．Dis∞very，synthesis，andinvivoactivi．[37)BigginsS．，MurrayA．．eta1．ThebuddingyeastproteinkinaseIPI1／tyofanewdasaofpyrazoloquina
4、zolinesasselectiveinhibitorsofau．AuroraallowstheabsenceoftensiontoactivatethespindiechecktoraBkinase[J3．Med．Chem．，2007，50(9)：2213—2224．point[J3．GenesDev．2001，15(23)：3118—3129．[323WilkinsonR．。OdedraR．，HeatonS．，eta1．AZD1152。asalectivein—[383GadeaB．。RudermanJ．V
5、．AurorakinaseinhibitorZM447439blockshibitorofauroraBkin0ze，inhibitshumantumorxenograftgrowthbychromosome-inducedspindleassembly，thecompletionofchromo—inducingapoptosis[J]．ClinCancerRes．．2007，13(12)：3682—3688．somecondensation．a(chǎn)ndtheestablishmentofthespindlein
6、tegrity(33JYangJ．，lkezocT．，NishiokaC．，eta1．AZD1152，anovelandselec．checkpointinxenopnseggextracts[J3．Mo1．BiolCel1．，2005，16(3)：raveauroraBkinaseinhibitor，inducesgrowtharresttapoptosis．a(chǎn)nd1305．1318．sensitizationfortubulindepolymerizingagentortopoisomeraseIIin—[
7、39]DitchfieldC．．KeenN．，TaylorS．Theipll／aurorakin~efamily：hibitorinhumanacuteleukemiacelhinvitroandinvivo[J]．Blood，methodsofinhibitionandfunctionalanalysisinmammaliancells[J32007，l10(6)：2034—2040．．MethodsMo1．Bio1．．2004，296：371—382．[343Ditchfleldc．．Jotx~oV．L．．
8、TigheA．，eta1．AuroraBcoupleschro．[403MarumotoT．。HondaS．，naraM．。eta1．AuroraAkinasemaintainsTIKIsomealignmemtwithanaphasebytargetingBUBR1．a(chǎn)ndCnepEthefidelityofearlyandlatemitoticeveWtsinHeLacels(J~
