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1、·傳統(tǒng)醫(yī)藥·中l(wèi)虱茜2014年9月20日第23卷第18期Trad#iona/medicineChimzPhnrmaceuticalsVo1.23,No.18,September20,2014益腎泄?jié)岱街委熗达L(fēng)性腎病并慢性腎衰竭32例李成偉,卜國林z,于鵬飛s(1.河北省承德隆化縣張三營中心衛(wèi)生院,河北承德068156;2.河北省承德隆化縣湯頭溝中心衛(wèi)生院,河北承德068155;3.河北省承德隆化縣七家鎮(zhèn)衛(wèi)生院,河北承德068154)摘要:目的觀察益腎泄?jié)岱街委熗达L(fēng)性腎病并慢性腎衰竭的療效。方法將64例痛風(fēng)性腎病并慢性腎衰竭患者隨機(jī)分為研究組和對照組,各32例。研究組患者
2、采用益腎泄?jié)岱街委?,對照組采用常規(guī)西藥治療,比較兩組患者的臨床療效及不良反應(yīng)。結(jié)果研究組的總有效率為84.37%,明顯高于對照組的68.75%(=4.11,P<0.05);治療后,研究組的血尿酸、血尿素氮、血肌酐、肌酐清除率等指標(biāo)與對照組比較,有明顯差異(t=4.65,3.25,5.01,3.97,P<0.05);兩組患者不良反應(yīng)發(fā)生率比較無明顯差異。結(jié)論益腎泄?jié)岱街委熗达L(fēng)性腎病并慢性腎衰竭的療效確切,不良反應(yīng)發(fā)生率低,值得臨床推廣。關(guān)鍵詞:益腎泄?jié)岱剑煌达L(fēng)性腎??;慢性腎衰竭中圖分類號:R285.6;R289.5文獻(xiàn)標(biāo)識碼:A文章編號:1006—4931(2014)18
3、—0096—02ClinicalEficacyofYishenXiezhuoDecoctioninTreatingGoutyNephropathyComplicatingC:hronicRenalFailurein32CasesLiChengwei,PuGuolin。,YuPengfei(J.ZhangsanyingCentralHealthCenterofLonghuaCounty,Chengde,Hebei,China068156;2.TangtougouCentralHealthCenterofLonghuaCounty,Chengde,Hebei,China06
4、8155;3.QijiazhenCentralHealthCenterofLonghuaCounty,Chengde,Hebei,China068154)Abstract:ObjectiveToinvestigatetheclinicaleffectofYishenXiezhuoDecoctionintreatinggoutynephropathycomplicatingchronicre—nalfailure.Methods64patientswithgoutynephropathycomplicatingchronicrenalfailurewererandomly
5、dividedintothestudygroupandthecontrolgroup,32casesineachgroup.ThestudygroupadoptedYishenXiezhuoDecoction,whilethecontrolgroupwasgiventheroutinewesternmedicinetherapy.TheclinicaleffectandadversereactionswerecomparedDetueenthetwogroups.ResultsThetotalef-fectiveratewas84.37%inthestudygroup,
6、whichwassignificantlyhigherthan68.75%inthecontrolgroup(:4.11,P<0.05);theindexesofblooduricacid,bloodureanitrogen,serumcreatinine,creatinineclearancerateaftertreatmentinthestudygrouphadstatisticallysignificantdifferencescomparedwiththecontrolgroup(t=4.65,3.25,5.01,3.97,P<0.05).Theoccurren
7、cerateofadversereactionshadnosignificantdifferencebetweenthetwogroups.ConclusionYishenXiezhuoDecoctionhasthedefiniteclinicaleffectintreatinggoutynephropathycomplicatingchronicrenalfailureandlowoccurencerateofadversereactions,whichiswo~hyofclinicalpromotion.Keywords:Yishen