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《康復(fù)新液聯(lián)合美沙拉秦灌腸液保留灌腸治療遠(yuǎn)段結(jié)腸潰瘍性結(jié)腸炎的療效觀察.pdf》由會(huì)員上傳分享,免費(fèi)在線閱讀,更多相關(guān)內(nèi)容在行業(yè)資料-天天文庫(kù)。
1、臨床醫(yī)學(xué)2015年3月第35卷第3期ClinicalMedicine,Mar.2015,Vo1.35,No.3·27·康復(fù)新液聯(lián)合美沙拉秦灌腸液保留灌腸治療遠(yuǎn)段結(jié)腸潰瘍性結(jié)腸炎的療效觀察何東凌(廣東省河源市人民醫(yī)院消化內(nèi)科,河源517000)【摘要】目的觀察康復(fù)新液聯(lián)合美沙拉秦灌腸液保留灌腸治療遠(yuǎn)段結(jié)腸潰瘍性結(jié)腸炎(UC)的療效。方法將140例住院治療的UC患者隨機(jī)分為兩組,每組70例,觀察組采用康復(fù)新液50ml加氯化鈉注射液50ml、美沙拉秦灌腸液4g/60ml,每晚保留灌腸1次,共4周;對(duì)照組采用美沙拉秦灌腸液4g/60ml每晚保留灌腸1次
2、,共4周。結(jié)果觀察組顯效36例,有效3O例,無(wú)效4例,總有效率為94.29%;對(duì)照組顯效23例,有效29例,無(wú)效18例,總有效率為74.29%,觀察組總有效率明顯高于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論康復(fù)新液聯(lián)合美沙拉秦保留灌腸治療遠(yuǎn)段結(jié)腸潰瘍性結(jié)腸炎療效穩(wěn)定可靠、安全性高、癥狀緩解快,值得臨床推廣應(yīng)用?!娟P(guān)鍵詞】遠(yuǎn)段結(jié)腸;潰瘍性結(jié)腸炎;保留灌腸;康復(fù)新液;美沙拉秦CurativeefectobservationofretentionenemaswithKangfuxinsolutioncombinedmesalazineinpat
3、ientswithdistalul-cerativecolitisHEDong—ling.Department0廠Gastroenterology,thePeople’SHospitalD廠Heyuan,Heyuan51700,China【Abstract】0bjectiveToevaluatetheeffectofretentionenemaswithmesalazinecombinedKangfuxinsolutiononpatientswithdistalulcerativecolitis(UC).MethodsOnehundredand
4、fortypatientswithdistalulcerativecolitisinaccordancewithinclusioncri-teriawererandomlydividedintotrialgroup(n=70)andcontrolgroup(n-70).rhepatientsintrialgroupweretreatedwithKangfux-insolution(50ml,and0.9%NaC150m1)combinedwithmesalazineenemas(4.060ml,everynight)for4weeks.Thep
5、atientsincontrolgroupweretreatedbymesalazineenemas(40g/60ml,everynight)for4weeks.ResultsIntrialgroup,36casesweremarkedlyefective,30caseswereeffective,4caseswereinefective,andthetotalefectiverateWas94.29%;Incontrolgroup,23ca-sesweremarkedlyefective.29caseswereefective,18cases
6、wereinefective,andthetotalefectiveratewas74.29%.田letotalef-fectiverateintrialgroupwashigherthanthatincontrolgroup.CondusionTheKangfuxinsolutioncombinedmesalazineenemashavetheadvantageofmoreefective,highersafety,lesstimeofsymptomsintreatmentofdistalulcerativecolitis.【Keywords
7、】Distalcolon;Ulcerativecolitis;Retentionenemas;Kangfuxinsolution;Mesalazine潰瘍性結(jié)腸炎(UC)病因不明確,與感染、環(huán)境、遺段UC(降結(jié)腸一乙狀結(jié)腸結(jié)腸炎,包括直腸炎)E3]。所有傳、免疫及心理精神等多種因素相互作用有關(guān),是一種患者在治療1個(gè)月前未使用過(guò)腎上腺皮質(zhì)激素及免疫原發(fā)性器官特異的自身免疫性疾病,病情遷延,治療棘抑制劑。排除對(duì)象包括爆發(fā)型、重度UC患者;依從性手,主要累及直腸和結(jié)腸黏膜及黏膜下層的彌漫性炎性差者;對(duì)水楊酸制劑過(guò)敏者;哺乳期婦女、孕婦;有胃腸病變,是
8、呈連續(xù)性分布的一種慢性的直腸和結(jié)腸非特異道手術(shù)史;感染性腸炎。治療前詳細(xì)向人選患者說(shuō)明情性炎性且病因尚不十分明確的疾病。近年來(lái)隨著結(jié)腸況,取得知情同意