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5、nalysis[J].MRAmJRoentgenol,2003,181Amifostine在惡性腫瘤放療中的應用馴夏紅強,金冶寧AdvancedresearchofAmifostineintheradiotherapytomalignanttumorsXIAHong—qiang,JINYe~ningOncologyDepartmentofRuijinHospitalaffiliatedtoShanghaiJiaotongUniversity,Shanghai200025,China.【Abstract】Radiotherapyisoneofvi
6、taltreatmentstomalignanttumors,butalwaysinevitablycomesupwithsideeffects.Thecellprotectoramifostinecanprotectma~ow,liverandkidneywithoutreducinganti—tumoreficiency.Subcutaneousorintrarectaladministrationismoresuitabletosomepatients.Theprotectioneffecthasdosedependencyandlimi
7、tation,cannotstillimprovethesurvivalrate.【Keywords】amifostine;cellprotector;tumor;radiotherapyModemOncology2009,17(o4):0774—0776【指示性摘要】放療是治療惡性腫瘤的主要治療方法之一,但往往不可避免地出現(xiàn)骨髓抑制等不良反應。細胞保護劑阿米福汀可以對骨髓、肝、腎等起保護作用而不影響抗腫瘤療效。皮下注射或直腸內給藥可能更適合某些病人。其細胞保護作用有一定劑量依賴性和局限性。尚不能影響腫瘤患者的生存率?!娟P鍵詞】阿米福汀;細胞保
8、護劑;腫瘤;放療【中圖分類號】R730.55【文獻標識碼】A【文章編號】1672—4992一(2009)04—0774—03放療,同手術、化療一樣,是