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1、授予單位代碼10089學號或申請?zhí)?0010010020中國圖書分類號R711.74碩士學位論文專業(yè)學位保留生育功能的宮頸病變治療方法選擇及預后研究生:白雪導師:王麗麗教授專業(yè):婦產科學二級學院:河北醫(yī)科大學第二醫(yī)院2018年3月目錄中文摘要············································································································1英文摘要······················································
2、······················································2英文縮寫············································································································3綜述保留生育功能的宮頸病變治療方法選擇及預后································4致謝·······························································
3、···················································17個人簡歷··········································································································18中文摘要保留生育功能的宮頸病變治療方法選擇及預后摘要近年來宮頸上皮內瘤變和宮頸癌患者有明顯年輕化趨勢，其中生育年齡婦女治療后迫切希望保留生育功能。因此許多學者對宮頸病變保留生育功能的術式、妊娠并發(fā)癥及妊娠結局等進行研究。CIN是宮頸癌進展過程中的
4、一個階段。CIN根據病變程度分為三級：CINⅠ、CINⅡ、CINⅢ，不同的病變分級對應不同的治療方法。CIN對妊娠無風險，對孕婦也不會構成立即風險，故選擇治療的時機很重要。早期宮頸癌（IA1期、IA2期及IB1期）患者可行保留生育功能的術式，研究證明保留生育功能的術式與傳統(tǒng)的宮頸癌術式相比，術后復發(fā)率沒有明顯差異。目前早期宮頸癌保留生育功能的術式主要有宮頸錐切術及RT。無論是宮頸錐切術還是RT，均會對患者的妊娠率及妊娠結局產生不同程度的影響，包括流產、絨毛膜羊膜炎、胎膜早破、早產、低出生體重兒及宮頸裂傷等。應積極尋找預防及治療的方法來提高術后患者的妊娠率及改善妊娠結局。
5、綜合國內外文獻，就宮頸上皮內瘤變及早期宮頸癌患者治療方法的選擇及預后進行闡述。關鍵詞：宮頸上皮內瘤變,宮頸癌,保留生育功能,宮頸錐切術,根治性宮頸切除術,妊娠結局1英文摘要ThetherapeuticmethodsandprognosisoffertilitypreservingsurgicalprocedurestotreatcervicallesionsABSTRACTTheageofpatientswithcervicalintraepithelialneoplasia(CIN)andcervicalcancershowsamoreapparenttendency
6、ofyounger.Mostofthemareofchildbearingage,whoareeagertopreservetheirfertilityaftertreatment.Inrecentyears,thereweremanystudiesonfertilitypreservingsurgicalprocedures,pregnantcomplicationsandpregnancyoutcomes.CINisaperiodduringthedevelopmentofcervicalcancer.CINisclassifiedintothreecategori
7、esaccordingtodifferentcervicallesiondegreesanddifferentdegreesarecorrespondingtodifferenttreatments.CINcarriesnoimmediatelyrisktothepregancy,soitisveryimportanttochoosethetreatmentopportunity.Thepatientswithearlycervicalcancercanchoosecervicalconizationandradicaltrachelec
