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1、授予單位代碼10089學(xué)號(hào)或申請(qǐng)?zhí)?0010010020中國圖書分類號(hào)R711.74碩士學(xué)位論文專業(yè)學(xué)位保留生育功能的宮頸病變治療方法選擇及預(yù)后研究生:白雪導(dǎo)師:王麗麗教授專業(yè):婦產(chǎn)科學(xué)二級(jí)學(xué)院:河北醫(yī)科大學(xué)第二醫(yī)院2018年3月目錄中文摘要············································································································1英文摘要······················································
2、······················································2英文縮寫············································································································3綜述保留生育功能的宮頸病變治療方法選擇及預(yù)后································4致謝·······························································
3、···················································17個(gè)人簡(jiǎn)歷··········································································································18中文摘要保留生育功能的宮頸病變治療方法選擇及預(yù)后摘要近年來宮頸上皮內(nèi)瘤變和宮頸癌患者有明顯年輕化趨勢(shì)，其中生育年齡婦女治療后迫切希望保留生育功能。因此許多學(xué)者對(duì)宮頸病變保留生育功能的術(shù)式、妊娠并發(fā)癥及妊娠結(jié)局等進(jìn)行研究。CIN是宮頸癌進(jìn)展過程中的
4、一個(gè)階段。CIN根據(jù)病變程度分為三級(jí)：CINⅠ、CINⅡ、CINⅢ，不同的病變分級(jí)對(duì)應(yīng)不同的治療方法。CIN對(duì)妊娠無風(fēng)險(xiǎn)，對(duì)孕婦也不會(huì)構(gòu)成立即風(fēng)險(xiǎn)，故選擇治療的時(shí)機(jī)很重要。早期宮頸癌（IA1期、IA2期及IB1期）患者可行保留生育功能的術(shù)式，研究證明保留生育功能的術(shù)式與傳統(tǒng)的宮頸癌術(shù)式相比，術(shù)后復(fù)發(fā)率沒有明顯差異。目前早期宮頸癌保留生育功能的術(shù)式主要有宮頸錐切術(shù)及RT。無論是宮頸錐切術(shù)還是RT，均會(huì)對(duì)患者的妊娠率及妊娠結(jié)局產(chǎn)生不同程度的影響，包括流產(chǎn)、絨毛膜羊膜炎、胎膜早破、早產(chǎn)、低出生體重兒及宮頸裂傷等。應(yīng)積極尋找預(yù)防及治療的方法來提高術(shù)后患者的妊娠率及改善妊娠結(jié)局。
5、綜合國內(nèi)外文獻(xiàn)，就宮頸上皮內(nèi)瘤變及早期宮頸癌患者治療方法的選擇及預(yù)后進(jìn)行闡述。關(guān)鍵詞：宮頸上皮內(nèi)瘤變,宮頸癌,保留生育功能,宮頸錐切術(shù),根治性宮頸切除術(shù),妊娠結(jié)局1英文摘要ThetherapeuticmethodsandprognosisoffertilitypreservingsurgicalprocedurestotreatcervicallesionsABSTRACTTheageofpatientswithcervicalintraepithelialneoplasia(CIN)andcervicalcancershowsamoreapparenttendency
6、ofyounger.Mostofthemareofchildbearingage,whoareeagertopreservetheirfertilityaftertreatment.Inrecentyears,thereweremanystudiesonfertilitypreservingsurgicalprocedures,pregnantcomplicationsandpregnancyoutcomes.CINisaperiodduringthedevelopmentofcervicalcancer.CINisclassifiedintothreecategori
7、esaccordingtodifferentcervicallesiondegreesanddifferentdegreesarecorrespondingtodifferenttreatments.CINcarriesnoimmediatelyrisktothepregancy,soitisveryimportanttochoosethetreatmentopportunity.Thepatientswithearlycervicalcancercanchoosecervicalconizationandradicaltrachelec
