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1、被動吸煙對急性睡眠剝奪大鼠行為的影響論文喻秋君,趙晶,劉芳娥,李靜,朱偉軍,李小康【Abstract】AIM:Toinvestigatetheeffectsofpassivesmoking(PS)onthebehaviorofsleepacutelydeprived(SD)rats.METHODS:Forty-nineratslydividedinto5groups:groupA:SD+PS24h,groupB:SD24h,groupC:SD+PS54h,groupD:SD54handgroupE:n
2、ormalcontrols.Differentperiodsofsleepdeprivationedinthe5groupsusingthe“floetimethestimulationofcigarettesmokeposedongroupAandgroupC.Theemotionalandbehavioralalterationsoftheratseasuredby“openfieldtest”.RESULTS:Theexplorativebehaviorinthe“openfield”ofgro
3、upBsignificantlyincreasedparedovementofgroupAsignificantlydecreasedparedovementofgroupCsignificantlydecreasedparedeofsleepdeprivation,theemotionalandbehavioralalterationsoftheratstendtobeginokepallmtion;openfieldtest;behavior【摘要】目的:研究被動吸煙(PS)對急性睡眠剝奪(SD)
4、大鼠行為的影響.方法:49只SD大鼠隨機分為5組,睡眠剝奪+被動吸煙24h組(A),睡眠剝奪24h組(B),睡眠剝奪+被動吸煙54h組(C).freel×30cm×40cm的鼠箱,其中有一直徑為25cm,高80cm的平臺,在平臺周邊注滿水,水溫保持在20℃左右,水面距平臺面約10cm.鼠在平臺上可自行飲食飲水.若其睡眠,則由于肌肉張力松弛而落入水中.在大鼠活動空間內持續(xù)40ilMedUniv,2002;22(10):888-890.[3]BradleyDY,ZhouJ,SmaginGN,etal.Sl
5、eepdeprivationbythe“Floemory[J].PhysiolBehav,1997;61(2):249-256.[4]馬太芳,郭賢熙,李芳蘭,等.被動吸煙對大鼠后代學習記憶功能及海馬內生長抑素含量的影響[J].中國現代醫(yī)學雜志,2000;2(15):48.MaTF,GuoXX,LiFL,etal.EffectsofpassivesmokingonlearningandmemorialfunctionandcontentofGHRIHinhippocampusofratsoffsprin
6、g[J].ChinModMed,2000;2(15):48.[5]OnenSH,AllouiA,EschalierA,etal.Vocalizationthresholdsrelatedtonoxiouspawpressurearedecreasedbyparadoxicalsleepdeprivationandincreasedaftersleeprecoveryinrat[J].NeurosciLett,2000;291(1):25-28.[6]宋國萍,苗丹民,皇甫恩.睡眠剝奪對大鼠學習和行為的影
7、響[J].第四軍醫(yī)大學學報,2000;21(6):663-666.