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1、被動(dòng)吸煙對(duì)急性睡眠剝奪大鼠行為的影響論文喻秋君,趙晶,劉芳娥,李靜,朱偉軍,李小康【Abstract】AIM:Toinvestigatetheeffectsofpassivesmoking(PS)onthebehaviorofsleepacutelydeprived(SD)rats.METHODS:Forty-nineratslydividedinto5groups:groupA:SD+PS24h,groupB:SD24h,groupC:SD+PS54h,groupD:SD54handgroupE:n
2、ormalcontrols.Differentperiodsofsleepdeprivationedinthe5groupsusingthe“floetimethestimulationofcigarettesmokeposedongroupAandgroupC.Theemotionalandbehavioralalterationsoftheratseasuredby“openfieldtest”.RESULTS:Theexplorativebehaviorinthe“openfield”ofgro
3、upBsignificantlyincreasedparedovementofgroupAsignificantlydecreasedparedovementofgroupCsignificantlydecreasedparedeofsleepdeprivation,theemotionalandbehavioralalterationsoftheratstendtobeginokepallmtion;openfieldtest;behavior【摘要】目的:研究被動(dòng)吸煙(PS)對(duì)急性睡眠剝奪(SD)
4、大鼠行為的影響.方法:49只SD大鼠隨機(jī)分為5組,睡眠剝奪+被動(dòng)吸煙24h組(A),睡眠剝奪24h組(B),睡眠剝奪+被動(dòng)吸煙54h組(C).freel×30cm×40cm的鼠箱,其中有一直徑為25cm,高80cm的平臺(tái),在平臺(tái)周邊注滿水,水溫保持在20℃左右,水面距平臺(tái)面約10cm.鼠在平臺(tái)上可自行飲食飲水.若其睡眠,則由于肌肉張力松弛而落入水中.在大鼠活動(dòng)空間內(nèi)持續(xù)40ilMedUniv,2002;22(10):888-890.[3]BradleyDY,ZhouJ,SmaginGN,etal.Sl
5、eepdeprivationbythe“Floemory[J].PhysiolBehav,1997;61(2):249-256.[4]馬太芳,郭賢熙,李芳蘭,等.被動(dòng)吸煙對(duì)大鼠后代學(xué)習(xí)記憶功能及海馬內(nèi)生長抑素含量的影響[J].中國現(xiàn)代醫(yī)學(xué)雜志,2000;2(15):48.MaTF,GuoXX,LiFL,etal.EffectsofpassivesmokingonlearningandmemorialfunctionandcontentofGHRIHinhippocampusofratsoffsprin
6、g[J].ChinModMed,2000;2(15):48.[5]OnenSH,AllouiA,EschalierA,etal.Vocalizationthresholdsrelatedtonoxiouspawpressurearedecreasedbyparadoxicalsleepdeprivationandincreasedaftersleeprecoveryinrat[J].NeurosciLett,2000;291(1):25-28.[6]宋國萍,苗丹民,皇甫恩.睡眠剝奪對(duì)大鼠學(xué)習(xí)和行為的影
7、響[J].第四軍醫(yī)大學(xué)學(xué)報(bào),2000;21(6):663-666.