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1、化痰祛瘀湯治療痰瘀阻滯型高脂血癥臨床觀察【關(guān)鍵詞】化痰祛瘀湯【摘要】忖的觀察化痰祛瘀湯治療高脂血癥(痰瘀阻滯型)的臨床療效和安全性。方法將140例患者隨機(jī)分為2組,各70例。治療組口服化痰祛瘀湯治療,對照組口服多烯康膠丸治療。2組均1個月為1個療程。觀察2組療效、治療前后癥狀積分及血脂各項(xiàng)指標(biāo)的變化。結(jié)果治療組總有效率91.43%,對照組總有效率72.86%,2組總有效率比較有顯著性差異(PvO.05)。治療組治療后總膽固醇、甘汕三酯、低密度脂蛋白和中供證候積分有明顯降低(PvO.05),高密度脂蛋白有明顯升高(PvO.05),且治療組降低總膽固醇、甘油三酯和升高高密度脂蛋口的療效
2、與對照組比較有顯著性差異(PV0.05),且臨床耒發(fā)現(xiàn)不良反應(yīng)。結(jié)論化痰祛瘀湯具有化痰降濁、活血祛瘀Z效,有明顯的調(diào)血脂作用,改善臨床癥狀顯著,且無毒副作用,值得臨床推廣使用?!娟P(guān)鍵詞】高脂血癥;痰瘀阻滯;中醫(yī)藥療法ClinicalobservationofHuatanquyudecoctiononhyperlipemiabasedondifferentiationofsplegmandbloodstagnaceWANGHaihong.FourthAffiliatedHospital,Medicalcollege,JinanUniversity,Guangzhou510220[Ab
3、stract]ObjectiveToobservetheclinicaleffectandsafetyofHuatanquyudecoctiononhyperlipemiabasedonthedifferentiationofsplegmandbloodstagnace?Methods140patientswererandomlydividedintothetreatmentgroup(n=70),whichwasadministretedHuatanquyudecoctionandthecontrolgroup(n=70)whichwasgivenepanolpill.Onemo
4、nthwasatreatmentcourseinthebothgroups.Theclinicalcurativeeffectiverate,symptomsscoresandvariousindexesofblood-lipidwereobservedbeforeandaftertreatment.ResultsThetotaleffectiveratewas91.43%intreatmentgroup,and72.86%incontrolgroup?Therewasasignificantdifferencebetweenthetwogroups(P<0.05).Compare
5、dwiththecontrolgroup,patientsinthetreatmentgroup,thelevelofcholesterol,triglyceride,lowdensitylipoproteinandthesymptomscoressignificantlyreducedaftertreatment(P<0.05),andthelevelofhighdensitylipoprotesignificantlyincreased(P<0.05).Therewasnoclinicaladversereactionobserved?ConclusionHuatanquyud
6、ecoctioncanregulateblood-lipid,improveclinicalsymptomsandhasnotoxicreaction.【Keywords]Hyperlipidemia;HuatanquyuDecoction;ClinicalResearch高脂血癥(hyperlipidemia)是指血漿脂質(zhì)濃度明顯超過正常人群水平,與動脈腳樣硬化(atherosclerosis)>冠狀動脈粥樣硬化性心臟病(以下簡稱冠心病)(coronaryheartdisease)>腦中風(fēng)、肥胖病、糖尿病的發(fā)生密切相關(guān)。目前降脂西藥品種很多,長期應(yīng)用有一定的不良反應(yīng)(如肝腎損傷、
7、橫紋肌溶解等)。中藥治療高脂血癥療效確切,價格低廉冃無毒副作用。2004-01^2005-06,筆者采川化痰祛瘀湯治療高脂血癥(痰瘀阻滯型)70例,并與單純西藥治療70例進(jìn)行對照觀察,現(xiàn)報告如下。1資料與方法1.1診斷標(biāo)準(zhǔn)西I矢診斷參照《血脂異常防治建議》[1]確定診斷。血清總膽固醇(TC)35.7mmol/L,甘汕三酯(TG)M1.8mmol/L,高密度脂蛋A(HDLC))男W1.04mmol/L,女W1.17mmol/L,低密度脂蛋白(LDLC)23.7mmol/