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1、ParagonimuswestermaniParagonimuswesternaniwasfirstdescribedfromtwoBengaltigerthathaddiedinzoosinEuropein1878.Duringthenext2years,infectionsbythisworminhumanswerefoundinFurmosa.Itwasveryquicklyfoundinthelungs,brain,andvisceraofhumansinJapan,Korea,andthePhilippines.
2、ThelifecyclewasworkedoutbyKobayashiandYokagawa.ThemajorfocusofinfectiontodayremainsintheOrient,includingIndiaandthePhilippines.ItalsoappearstobeendemicthroughouttheEastIndies,NewGuinea,theSolomonIslands,Samoa,westernAfrica,Peru,Colombia,andVenezuela.Thetaxonomyoft
3、hegenusisdifficult,andsomeofthesereportsmaybeofother,closelyrelatedspecies.Paragonimiasisisanexcellentexampleofzoonosis.并殖吸蟲Paragonimuswestermani衛(wèi)氏并殖吸蟲Pagumogonimusskrjabini斯氏貍殖吸蟲人獸共患型獸主人次型衛(wèi)氏并殖吸蟲(肺吸蟲)Paragonimuswestermani卵巢子宮睪丸卵黃腺一、形態(tài)成蟲卵黃腺腸支口吸盤睪丸腹吸盤子宮中等大小不規(guī)則橢圓形金黃色
4、1個(gè)卵細(xì)胞、10多個(gè)卵黃細(xì)胞卵殼厚薄不一卵蓋大、常傾斜、也可缺如大小形狀顏色卵殼內(nèi)容物其他蟲卵卵細(xì)胞卵蓋卵殼卵黃細(xì)胞毛蚴胞蚴川卷螺成蟲(肺)人、犬、貓、虎等囊蚴入水(痰、糞便)體內(nèi)移行穿腸壁肺穿膈肌胸腔腹腔二、生活史Lifecycle母雷蚴子雷蚴尾蚴溪蟹滯育童蟲(野豬、野鼠)卵竄擾肝、腦、皮下1、感染期:2、感染方式:3、寄生部位:4、終宿主:5、保蟲宿主:囊蚴生吃含囊蚴的溪蟹、轉(zhuǎn)續(xù)宿主的肉(豬肉)犬、貓、虎人生活史特點(diǎn):肺、異位寄生三、致病(pathogenesis)急性期慢性期膿腫期囊腫期纖維疤痕期Theearly,i
5、nvasionstagesofparagonimiasiscausefewornosymptomaticpathologicalconditions.Onceinalungoranectopicsite,thewormstimulatesconnectivetissueproliferationthateventuallywillenshrouditinabrownishorbluishcapsule.Suchcapsulesoftenulcerateandhealslowly.Eggsinsurroundingtissu
6、eswillthemselvesbecomecentersofpseudotubercles.Wormsinthespinalcordareknowntocauseparalysis,whichsometimesistotal.FatalcasesofParagonimusinthehearthavebeenrecorded.Cerebralcaseshavethesameresultsasthoseofcerebralcysticercosis.Pulmonarycasesusuallycausechestsymptom
7、s,withbreathingdifficulties,chroniccough,andsputumcontainingbloodorbrownishstreaks.Fatalcasesarecommon.三、致病(pathogenesis)臨床分型胸肺型腹型皮下包塊型腦脊髓型亞臨床型其他型錄像四、診斷(diagnosis)病原學(xué)診斷免疫學(xué)診斷痰檢蟲卵活組織檢查糞檢蟲卵ELISA酶聯(lián)免疫吸附試驗(yàn)皮內(nèi)試驗(yàn)直接涂片法五、流行與防治(EndemityandPrevention)流行毛蚴胞蚴川卷螺成蟲(肺)人、犬、貓、虎等囊蚴入水
8、(痰、糞便)母雷蚴子雷蚴尾蚴溪蟹滯育童蟲(野豬、野鼠)卵123傳染源卵巢子宮睪丸卵黃腺一、形態(tài)成蟲斯氏貍殖吸蟲Pagumogonimusskrjabini衛(wèi)氏并殖吸蟲第一中間宿主川卷螺斯氏貍殖吸蟲擬釘螺終宿主人,犬,虎果子貍幼蟲移行癥第十一章絳蟲(Cestode)第一節(jié)概 論P(yáng)1312、蟲體分節(jié)3、雌雄