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1、ParagonimuswestermaniParagonimuswesternaniwasfirstdescribedfromtwoBengaltigerthathaddiedinzoosinEuropein1878.Duringthenext2years,infectionsbythisworminhumanswerefoundinFurmosa.Itwasveryquicklyfoundinthelungs,brain,andvisceraofhumansinJapan,Korea,andthePhili
2、ppines.ThelifecyclewasworkedoutbyKobayashiandYokagawa.ThemajorfocusofinfectiontodayremainsintheOrient,includingIndiaandthePhilippines.ItalsoappearstobeendemicthroughouttheEastIndies,NewGuinea,theSolomonIslands,Samoa,westernAfrica,Peru,Colombia,andVenezuela.
3、Thetaxonomyofthegenusisdifficult,andsomeofthesereportsmaybeofother,closelyrelatedspecies.Paragonimiasisisanexcellentexampleofzoonosis.并殖吸蟲Paragonimuswestermani衛(wèi)氏并殖吸蟲Pagumogonimusskrjabini斯氏貍殖吸蟲人獸共患型獸主人次型衛(wèi)氏并殖吸蟲(肺吸蟲)Paragonimuswestermani卵巢子宮睪丸卵黃腺一、形態(tài)成蟲卵黃腺腸支口吸
4、盤睪丸腹吸盤子宮中等大小不規(guī)則橢圓形金黃色1個卵細胞、10多個卵黃細胞卵殼厚薄不一卵蓋大、常傾斜、也可缺如大小形狀顏色卵殼內容物其他蟲卵卵細胞卵蓋卵殼卵黃細胞毛蚴胞蚴川卷螺成蟲(肺)人、犬、貓、虎等囊蚴入水(痰、糞便)體內移行穿腸壁肺穿膈肌胸腔腹腔二、生活史Lifecycle母雷蚴子雷蚴尾蚴溪蟹滯育童蟲(野豬、野鼠)卵竄擾肝、腦、皮下1、感染期:2、感染方式:3、寄生部位:4、終宿主:5、保蟲宿主:囊蚴生吃含囊蚴的溪蟹、轉續(xù)宿主的肉(豬肉)犬、貓、虎人生活史特點:肺、異位寄生三、致?。╬athogenesis
5、)急性期慢性期膿腫期囊腫期纖維疤痕期Theearly,invasionstagesofparagonimiasiscausefewornosymptomaticpathologicalconditions.Onceinalungoranectopicsite,thewormstimulatesconnectivetissueproliferationthateventuallywillenshrouditinabrownishorbluishcapsule.Suchcapsulesoftenulceratea
6、ndhealslowly.Eggsinsurroundingtissueswillthemselvesbecomecentersofpseudotubercles.Wormsinthespinalcordareknowntocauseparalysis,whichsometimesistotal.FatalcasesofParagonimusinthehearthavebeenrecorded.Cerebralcaseshavethesameresultsasthoseofcerebralcysticerco
7、sis.Pulmonarycasesusuallycausechestsymptoms,withbreathingdifficulties,chroniccough,andsputumcontainingbloodorbrownishstreaks.Fatalcasesarecommon.三、致病(pathogenesis)臨床分型胸肺型腹型皮下包塊型腦脊髓型亞臨床型其他型錄像四、診斷(diagnosis)病原學診斷免疫學診斷痰檢蟲卵活組織檢查糞檢蟲卵ELISA酶聯(lián)免疫吸附試驗皮內試驗直接涂片法五、流行與防治
8、(EndemityandPrevention)流行毛蚴胞蚴川卷螺成蟲(肺)人、犬、貓、虎等囊蚴入水(痰、糞便)母雷蚴子雷蚴尾蚴溪蟹滯育童蟲(野豬、野鼠)卵123傳染源卵巢子宮睪丸卵黃腺一、形態(tài)成蟲斯氏貍殖吸蟲Pagumogonimusskrjabini衛(wèi)氏并殖吸蟲第一中間宿主川卷螺斯氏貍殖吸蟲擬釘螺終宿主人,犬,虎果子貍幼蟲移行癥第十一章絳蟲(Cestode)第一節(jié)概 論P1312、蟲體分節(jié)3、雌雄