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1、心先安對急性心肌梗死患者左室舒張功能的影響作者:盧海崧梁中華張偉華【關(guān)鍵詞】心肌梗死【摘要】目的觀察心先安對急性心肌梗死(AMI)患者左室舒張功能的影響。方法96例AMI患者隨機(jī)分為兩組,對照組采用常規(guī)方法治療;治療組在常規(guī)方法治療的基礎(chǔ)上加用心先安注射液90~120mg加入5%葡萄糖注射液(或生理鹽水)250ml中靜脈滴注,每日1次。兩組療程均為2周。分別于治療前和治療后2周行心臟超聲心動(dòng)圖,測定每搏量、心排血量、心排血指數(shù)、左心室射血分?jǐn)?shù)、室壁增厚率、左心室短軸縮短率等。結(jié)果治療2周后,治療組患者的心排血量、每搏量、心排血指數(shù)、左心室射血分?jǐn)?shù)、室壁增厚率、左心室短軸縮短率改善明
2、顯,與治療前比較差異有顯著性(P<0.05),其中每搏量、左心室射血分?jǐn)?shù)與對照組比較差異亦有顯著性(P<0.05);對照組以上指標(biāo)治療后雖有改善,但與治療前比較差異無顯著性(P>0.05)。結(jié)論在常規(guī)方法治療AMI的基礎(chǔ)上用心先安注射液,能有效地改善患者的左室舒張功能,從而改善患者的左心功能。關(guān)鍵詞心先安注射液左室舒張功能急性心肌梗死超聲心動(dòng)圖9Effectsofmeglumineadenosinecyclophosphateinjectiononleftventriclediastolefunctionofpatientswithacutemyocardiali
3、nfarction.【Abstract】ObjectiveToobservemeglumineadenosinecyclophosphateinjectioninfluenceontheacutemy-ocardialinfarction(AMI)patient'sleftventriclediastolefunction.Methods96AMIpatientswasdividedintotwogroupsatrandom,contrastingtothegroupadoptstheconventionalmethodstotreat.90~120mgofmeglumineade
4、no-sinecyclophosphateInjectiondilutedin250mlof5%glucoseinjectionornormalsalinewasinstilledonthebasisofroutinemethodintreatmentgrouponceaday.Theechocardiographywasusedtodeterminethestrokeoutput,cardiacoutput,cardiacindex,leftventricularejectionfraction,ventricularthickeningrate,andleftventricul
5、arminoraxisshort-eningrate.ResultsThecardiacoutput,strokeoutput,cardiacindex,leftventricularejectionfraction,ventricularthickeningrateandleftventricularminoraxisshorteningratewereimprovedmarkedlyintreatmentgroupaftertwoweekswhichhadsignificantdifferencecomparedwiththoseofpretreatment(P<0.05
6、).Andthestrokeoutput,left9ventricularejectionfractionwereimprovedsignificantlycomparedwiththoseofthecontrolgroup.Abovementionedin-dexeswereslightlychangedinthecontrolgroup(P<0.05).ConclusionThemeglumineadenosinecyclophosphateinjectionadministeredwithconventionaltreatmentcouldeffectivelyimpr
7、ovetheleftventriculardiastolefunction.Keywordsmeglumineadenosinecyclophosphateinjectionleftventriclediastolefunctionacutemyocardialinfarctionechocardiography急性心肌梗死(AMI)患者經(jīng)常有不同程度的心功能改變,嚴(yán)重者出現(xiàn)急性左心衰竭,而使用強(qiáng)心藥如毒毛苷有其禁忌證,往往易影響患者的心功能和預(yù)后。本研究應(yīng)用環(huán)磷酸腺