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《雙歧桿菌乳桿菌三聯(lián)活菌片防治小兒抗生素相關(guān)性腹瀉的臨床研究》由會員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在行業(yè)資料-天天文庫。
1、雙歧桿菌乳桿菌三聯(lián)活菌片防治小兒抗生素相關(guān)性腹瀉的臨床研究【摘要】目的探討雙歧桿菌乳桿菌三聯(lián)活菌片防治小兒抗生素相關(guān)性腹瀉(AAD)的臨床療效。方法選取2010年3月至2013年2月本院呼吸道感染患兒300例，首先按照年齡大小分為A組(1個月～1歲)140例，B組(1～3歲)160例，AB兩組內(nèi)再隨機(jī)分成觀察組150例(A組:70例，B組:80例)與對照組150例(A組:70例，B組:80例)。對照組應(yīng)用抗生素治療呼吸道感染，出現(xiàn)腹瀉后給予常規(guī)治療;觀察組在應(yīng)用抗生素治療的同時給予雙歧桿菌乳桿菌三聯(lián)活菌片，出現(xiàn)腹瀉后在常規(guī)治療的基礎(chǔ)上繼續(xù)
2、服用該藥物。觀察指標(biāo)包括腹瀉發(fā)生率、治療總體有效率、腹瀉持續(xù)時間三項(xiàng)。結(jié)果①觀察組腹瀉發(fā)生率明顯的低于對照組，腹瀉治療總體有效率明顯的高于對照組，腹瀉持續(xù)時間明顯的短于對照組，差異有統(tǒng)計(jì)學(xué)意義(P＜0.05);②B組中觀察組的腹瀉發(fā)生率明顯低于A組中的觀察組，差異有統(tǒng)計(jì)學(xué)意義(P＜0.05)。結(jié)論雙歧桿菌乳桿菌三聯(lián)活菌片防治小兒抗生素相關(guān)性腹瀉臨床療效顯著，尤其對于1～3歲的小兒AAD預(yù)防效果更加突出，值得臨床推廣?！娟P(guān)鍵詞】雙歧桿菌乳桿菌三聯(lián)活菌片;抗生素相關(guān)性腹瀉;小兒TheclinicalresearchOfpediatricant
3、ibioticassociateddiarrheapreventedandtreatedbybifidobacteri-umlactobacillustriplelivingbacteriumtabletQUShu-sheng．ShandongFeichengMiningCenterHospital，Tai’an271608，China【Abstract】ObjectiveDiscusstheclinicaleffectofpediatricantibioticassociateddiarrhea(AAD)pre-ventedandtre
4、atedbybifidobacteriumlactobacillustriplelivingbacteriumtablet．MethodsSelectionourhos-pitalpediatricrespiratorytractinfectionchildren300casesfromMarch2010toFebruary2013，firstlydividedintogroupA(1month～1yearold)140casesandgroupB(1～3yearold)160casesaccordingtotheage;secondly
5、randomlydividedintoobservationgroup(groupA:70casesandgroupB:80cases)andcontrolgroup150cases(groupA:70casesandgroupB:80cases)withintheABgroups．Controlgroupgivenantibioticstreatrespiratorytractinfection，givenconventionaltreatmentafterdiarrheaappear;Observationgroupgivenbifi
6、dobacteriumlactobacillustriplelivingbacteriumtabletatthetimeofapplicationofantibiotics，continuetak-ingthisdrugonthebasisofconventionaltreatmentafterdiarrheaappear．Observationindexesincludingthein-cidenceofdiarrhoea，totaleffectiverate，durationofdiarrhoea．Ｒesults①Theinciden
7、ceofdiarrheaofobser-vationgroupwasobviouslylowerthanthecontrolgroup，diarrheatreatmentoveralleffectivenessobvioushigherthancontrolgroup，thedurationofdiarrheasignificantlyshorterthanthecontrolgroup，withsignificantdiffer-ence(P＜0.05);②theIncidenceofdiarrheaofobservationgroup
8、ingroupBwasobviouslylowerthantheob-servationgroupingroupA，withsignificantdifference(P＜0.05)．Conc
