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《雙歧桿菌乳桿菌三聯(lián)活菌片防治小兒抗生素相關(guān)性腹瀉的臨床研究》由會(huì)員上傳分享,免費(fèi)在線閱讀,更多相關(guān)內(nèi)容在學(xué)術(shù)論文-天天文庫。
1、雙歧桿菌乳桿菌三聯(lián)活菌片防治小兒抗生素相關(guān)性腹瀉的臨床研究【摘要】目的探討雙歧桿菌乳桿菌三聯(lián)活菌片防治小兒抗生素相關(guān)性腹瀉(AAD)的臨床療效。方法選取2010年3月至2013年2月本院呼吸道感染患兒300例,首先按照年齡大小分為A組(1個(gè)月~1歲)140例,B組(1~3歲)160例,AB兩組內(nèi)再隨機(jī)分成觀察組150例(A組:70例,B組:80例)與對(duì)照組150例(A組:70例,B組:80例)。對(duì)照組應(yīng)用抗生素治療呼吸道感染,出現(xiàn)腹瀉后給予常規(guī)治療;觀察組在應(yīng)用抗生素治療的同時(shí)給予雙歧桿菌乳桿菌三聯(lián)活菌片,出現(xiàn)腹瀉后在常規(guī)治療的基礎(chǔ)上繼續(xù)服用該藥物。觀察指標(biāo)包括腹瀉發(fā)生率、治療總體
2、有效率、腹瀉持續(xù)時(shí)間三項(xiàng)。結(jié)果①觀察組腹瀉發(fā)生率明顯的低于對(duì)照組,腹瀉治療總體有效率明顯的高于對(duì)照組,腹瀉持續(xù)時(shí)間明顯的短于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P<0.05);②B組中觀察組的腹瀉發(fā)生率明顯低于A組中的觀察組,差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論雙歧桿菌乳桿菌三聯(lián)活菌片防治小兒抗生素相關(guān)性腹瀉臨床療效顯著,尤其對(duì)于1~3歲的小兒AAD預(yù)防效果更加突出,值得臨床推廣?!娟P(guān)鍵詞】雙歧桿菌乳桿菌三聯(lián)活菌片;抗生素相關(guān)性腹瀉;小兒TheclinicalresearchOfpediatricantibioticassociateddiarrheapreventedandtreated
3、bybifidobacteri-umlactobacillustriplelivingbacteriumtabletQUShu-sheng.ShandongFeichengMiningCenterHospital,Tai’an271608,China【Abstract】ObjectiveDiscusstheclinicaleffectofpediatricantibioticassociateddiarrhea(AAD)pre-ventedandtreatedbybifidobacteriumlactobacillustriplelivingbacteriumtablet.Meth
4、odsSelectionourhos-pitalpediatricrespiratorytractinfectionchildren300casesfromMarch2010toFebruary2013,firstlydividedintogroupA(1month~1yearold)140casesandgroupB(1~3yearold)160casesaccordingtotheage;secondlyrandomlydividedintoobservationgroup(groupA:70casesandgroupB:80cases)andcontrolgroup150ca
5、ses(groupA:70casesandgroupB:80cases)withintheABgroups.Controlgroupgivenantibioticstreatrespiratorytractinfection,givenconventionaltreatmentafterdiarrheaappear;Observationgroupgivenbifidobacteriumlactobacillustriplelivingbacteriumtabletatthetimeofapplicationofantibiotics,continuetak-ingthisdrug
6、onthebasisofconventionaltreatmentafterdiarrheaappear.Observationindexesincludingthein-cidenceofdiarrhoea,totaleffectiverate,durationofdiarrhoea.Results①Theincidenceofdiarrheaofobser-vationgroupwasobviouslylowerthanthecontrolgroup,diarrheatreatmentoveralleffectivenessobvioushigherthancontrolgro
7、up,thedurationofdiarrheasignificantlyshorterthanthecontrolgroup,withsignificantdiffer-ence(P<0.05);②theIncidenceofdiarrheaofobservationgroupingroupBwasobviouslylowerthantheob-servationgroupingroupA,withsignificantdifference(P<0.05).Conc