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1、●’?！ぁ?、It,，‘‘!二L．．■．．一tk目錄中文摘要????????????????????????1英文摘要????????????????????????4研究論文鹽酸氨溴索滲透泵控釋制劑的研制弓I言”一”“一””一””一””一一“一””一············”·····一”·······““····9第一部分鹽酸氨溴索雙層滲透泵片的制備前言??????????···????????????···100日¨看”一”“一””一””一””一””一””一”“一””一”“““”一””一“l(fā)材料與方法?????????????????????1l結(jié)果···?······?···?····
2、··?············?···?·····················20附圖···?···??···?···??···?···???????······?···25附表????????????????????????39討{侖“一”“一·一““··““·”一”“一······················一“·“····””·46d、結(jié)···········?·?······???····!??····························48參考文獻(xiàn)??????????????????????48第二部分鹽酸氨溴索滲透泵膠囊的制備前言“一”“一”?”一””一”?”
3、．．．．”一”?”．．““一”?”一“?．．·5一O刖吾“一”“一””一””一”“”””““”一””””“一””一””一“”一”材料與方法?????????????????????51結(jié)果??··一··?···?······?··一········?·········”一·········”“·54附圖···?···???????···?????????·?··?···57附表??????????????????????．．．?66討論············································???·-···············”69小結(jié)··········
4、···??···································“·············69參考文獻(xiàn)??????????????????????70第三部分鹽酸氨溴索滲透泵制劑的質(zhì)量評價’前言···?????????···?????????···??···7l剛舌”一””一”“一”“一””一”“一?一“一””?一”一一””一””一”’7l材料與方法??????：??????????????··71結(jié)果···?···??·········???·??··?··???················75附圖????????????????????????77附表???????
5、??????????????··，??85討論··??·····················?··············???····????·87小結(jié)···············???··??···-?-·····?···?···”一·····?···87參考文獻(xiàn)??????????????????????88第四部分鹽酸氨溴索滲透泵制劑Beagle犬體內(nèi)藥動學(xué)研究前言“一””“”．．一””一”?“一“?????”一””一“?”一””·8—9一月U吾“一””“”“一””一”?“一“?“一“””“”“””一““一””一”材料與方法?????????????????????89結(jié)果··
6、····?·····················?····?·····?···?············“····93附圖···?·??···························································96附表···“一“”一“··一···”·””··········?“一“·””一““．．““．．一···100討{念“一””一”一?一””一””·······?“一”··一··””””一““一”···105以、結(jié)”一””一”一一”一一””一””一””???一””一””一””一”一·106參考文獻(xiàn)?????????????????????
7、?107結(jié)論”一””一”一一””一”．．一“····“”一””一?一“一””一””一””·108綜述難溶性藥物雙層滲透泵片的研究進(jìn)展??????????109致謂
8、-···········································?·························1l6個人簡歷???????????????????????117中文摘要鹽酸氨溴索滲透泵控釋制劑的研制摘要
