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2、分內(nèi)容編入有關(guān)數(shù)據(jù)庫進(jìn)行檢索,可以采用影印、縮印或其他復(fù)制手段保存論文和匯編本學(xué)位論文。(保密論文在解密后應(yīng)遵守此規(guī)定)論文作者簽名:<茳逢三導(dǎo)師簽名:勉日期:山東大學(xué)博:卜學(xué)位論文目錄中文摘要??????????????????????????????1英文摘要??????????????????????????????6符號說明?????????????????????????????1,3前言”?????·······““····?一..???..””?????”“????一。1b一刖吾”???
3、??..”“”“”””?”“???”“??????“????”第一部分TNF—Q對牙周膜干細(xì)胞和骨髓間充質(zhì)干細(xì)胞增殖和成骨分化影響的研究?··???????·??·····??????····?··??·???·?????··19材料和方法????????????????????????????21結(jié)果?··??????·????····??···???????··?????31討論?···00g@?·??·?·???一????????????????·41第二部分TNF-Q對牙周膜干細(xì)胞和骨髓間充質(zhì)
4、干細(xì)胞增殖和成骨分化影響的信號通路研究????????????????????????????45材料和方法????????????????????????????46結(jié)果???···?·?·····????··????????????????·55討論????????????“?????????一·??????·61第三部分TNF-Q對小鼠骨創(chuàng)傷修復(fù)影響的研究?????????????65材料和方法????????????????????????????66結(jié)果???????···?????????
5、????????????69討論??··?????·??????????·?????·····?··?·?72全文總結(jié)?????????????????????????????74參考文獻(xiàn)?????????????????????????????75致謝?··?·??·?··????“··”?????···??·??”·????一80攻讀博士學(xué)位期間發(fā)表論文統(tǒng)計(jì)???????????????????82攻讀博士學(xué)位期間發(fā)表或待發(fā)表論文Roleofbonesialopretein(BSP)inosteo
6、clast—mediatedosteolyticmetastasis····························?···································83Dose?!痵pecificeffectsoftumornecrosiSfactoralphaonosteogenicdifferentiationofmesenchymalstemcelis??92山東人學(xué)博士學(xué)位論文CoNTENTSChineseAbstract····················
7、···································-······················1EnglishAbstract?···???”??????????????????····6Symbolicdescription???·??????????????·?????·13Introduction?????···?????????···000??????????15PartIEffectsofTNF—Qonosteogenicdifferentiationofhumanpe
8、riodontal1igamentstemcells(hPDLSCs)andmesenchymalstemcellsST2MaterialSandmethods????????··??????????????·2lResults······000··············································································31Discussion????????????????