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1、耳穴治療高脂血癥隨機對照臨床研究文獻Meta分析李歡李桂平天津中醫(yī)藥大學天津中醫(yī)藥大學第一附屬醫(yī)院針灸摘要:目的系統(tǒng)評價耳穴治療高脂血癥的臨床療效。方法計算機檢索中國知網(wǎng)數(shù)據(jù)庫(CNKI)、維普全文期刊數(shù)據(jù)庫(VIP)、萬方數(shù)據(jù)庫(WanFangData)、PubMed、WebofScience>EMbase>MEDLINE(Ovid)和CochraneLibrary等數(shù)據(jù)庫,搜集耳穴治療高脂血癥的相關臨床隨機對照試驗(RCT),檢索時限均從建庫至2016-12-3K由2名研究者獨立篩選文獻、提取資料和評價納入研究的偏倚風險后,采用RevMan5.3軟件進行Meta分析。
2、結果共納入9篇隨機對照試驗,包括1115例患者。Meta分析結果:從總有效率來看,耳針聯(lián)合中西藥與單純中西藥降脂療效相似,耳穴聯(lián)合改變生活方式的降脂療效優(yōu)于單純改變生活方式降脂,耳針與西藥降脂療效相似,耳穴聯(lián)合體針的降脂療效優(yōu)于單純體針降脂。結論耳穴降脂有一定療效且相對安全。但因納入試驗數(shù)有限且文獻質量較低,需要設計更嚴格的隨機對照試驗來進一步驗證上述結論。關鍵詞:耳穴貼壓;高脂血癥;穴位療法;Met。分析;作者簡介:李歡(1991—),女,碩士研究生在讀。研究方向:針灸推拿學。收稿日期:2017-07-05Randomizedcontrolledtrialsofauri
3、cularpointforhyperlipidemia:AMeta-analysisLIHuanLIGuipingTianjinUniversityofTraditionalChineseMedicine;Abstract:ObjectiveTosystematicallyassesstheclinicaleffectsofauricularpointonthetreatmentofhyperlipidemia.MethodsWeelectronicallysearcheddatabasesincludingCNKI,VIP,WanFangData,PubMed,Webo
4、fScience,EMbase,MEDTTNE(Ovid),andCochraneLibrarytocollectremdomizcdcontrolledtrials(RCT)ofauricularpointforhyperlipidemiafrominceptiontoDecember31,2016.Tworeviewersindependentlyscreenedliterature,extracteddataandassessedtheriskofbiasofincludedstudies.Then,meta-analysiswasperformedbyusingR
5、evMan5.3software.ResultsAtotalof91iteraturesand1115patientswereincluded.TheResultsofMcta-analysisindicated:intcrmsofthetotedeffectivcrate,theauricularneedlecombinedwithChineseandwesternmedicine,andsimpleChineseandwesternmedicinehavesimilareffectsonlipid-lowering.Thelipid-loweringeffectofa
6、uricularpointcombinedwithchangingthe1ifestyleisbetterthansimplychangingthe1ifestyle.Auricularpointandwesternmcdicinchavesimilareffectsonlipid-lowering.Thelipid-loweringeffectofauricularpointcombinedwithbodyacupunctureissuperiortothesimplybodyacupuncture.ConelusionAuriculariapointhasacerta
7、inefficacyandrelativelysafeon1ipid-lowering.However,duetothelimitednumberoftrialsandthelowqualityoftheliterature,amorerigorousremdomizedcontrolledtrialisneededtofurthervalidatetheaboveConclusions.Keyword:Auricularpressure;Hyperlipemia;Acupointtherapy;Metaanalysis;Re