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1、中華普外科手術(shù)學(xué)雜志(電子版)2011年l1月第5卷第4期ChinJ0perProcGenSurg(ElectronicEdition),Nov2011,Vol5,No.4.論著.胰體尾切除術(shù)后胰瘺的相關(guān)性因素分析郭石1、獻(xiàn)民戴顯偉【摘要】目的探討胰體尾切除術(shù)后胰瘺發(fā)生的相關(guān)性因素。方法回顧性總結(jié)了82例行胰體尾切除的患者術(shù)前、術(shù)中操作以及術(shù)后并發(fā)癥和死率發(fā)生的情況,并分析和術(shù)后胰瘺發(fā)生的相關(guān)性素。結(jié)果術(shù)后有36名患者出現(xiàn)并發(fā)癥占43.9%(36/82)。其中胰瘺是最常見(jiàn)的并發(fā)癥,發(fā)生率為37.8%(31/82)其中是否結(jié)扎主胰管和術(shù)后胰瘺的發(fā)生具有
2、明顯的相關(guān)性(P=0.010),而性別、年齡、足并存糖尿病、胰腺的質(zhì)地、術(shù)中失血量、是否預(yù)防性應(yīng)用奧曲肽、是否用生物膠封閉胰腺斷端、術(shù)后低蛋白m癥和是否聯(lián)合其它臟器切除均和胰瘺的發(fā)生無(wú)明顯的相關(guān)性。結(jié)論胰體尾切除術(shù)后最常見(jiàn)的并發(fā)癥仍然是胰瘺,術(shù)中單獨(dú)結(jié)扎胰管可以減少胰瘺的發(fā)生率。【關(guān)鍵詞】胰腺腫瘤;胰腺切除術(shù);胰腺瘺;胰體尾切除RiskfactorsforpancreaticfistulaafterdistalpancreatectomyGUOShi,BUXian—rain,DAIXian—wei.DepartmentofGeneralSurgery
3、,SujiatunCentralHospital,ShenyangllOlO1,China;DepartmentofHepato—biliaryandPancreaticOncologySurgeryShenjingHospital,Shenyang110004,ChinaCorrespondingauthor:GUOShi,Email:g#h2002@hotmail.coin【Abstract】ObjectiveToinvestigatepotentialriskfactorsforpancreatic:fistula(PF)afterdistal
4、pancreatectomy.MethodsWeretrospectivelyreviewed82patientswhohadundergonedistalpancreatec—tomy.Theperioperativedataandpostoperativemorbidityandmortalitywerecollected.Theriskthctorsf(1rpostoperativePFwereanalyzed.ResultsOfthe82patientsenrolledinthestud),36patients(43.9%)developed
5、postoperativecomplications.PFwasthemostcoininoncomplicationwithanincidenceof37.8%(31/82).LigationofthenlainpancreaticductduringtheoperationcouldsignificantlydecreasetheincidenceofPF(P=0.010).Theotherfactorsincludingage,gender,preoperativediabetes,normalorfibroticpancreaticstump
6、,intraoperativebloodloss,prophylacticuseofoctreotide,reinforcementofpancreaticstumpwithfibringlue,postoperativelowalbuminlevelandmultivisceralresectionwerenotcloselyrelatedtotheincidenceofPF.ConclusionsPFisstilltbemostcommoncomplicationafterdistalpancreateetomy.Electiveligation
7、ofthemainpancreaticductcouldlowertheincidenceofpostoperativePF.【Keywords】Pancveaticneoplasms;Pancreatectomy;Pancreaticfistula;Distalpancreatectomy胰體尾切除術(shù)是治療胰腺體尾部腫瘤、慢性炎資料和方法癥及創(chuàng)傷的常規(guī)術(shù)式,隨著手術(shù)技術(shù)和圍手術(shù)期管2006年1月至2010年2月中國(guó)醫(yī)科大學(xué)附屬理水平的不斷提高,其術(shù)后死亡率和并發(fā)癥發(fā)生率盛京醫(yī)院和蘇家屯中心醫(yī)院行胰體尾切除病例共已經(jīng)大大降低,但是作為術(shù)后主要并發(fā)癥之
8、一的胰82例,其中男性48例,女性34例,年齡在31~79歲瘺仍然是閑擾外科醫(yī)生的一個(gè)難題,雖然很多外科之間