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1、ExpertOpiniononPharmacotherapyISSN:1465-6566(Print)1744-7666(Online)Journalhomepage:http://www.tandfonline.com/loi/ieop20Thetreatmentofgastroparesis,constipationandsmallintestinalbacterialovergrowthsyndromeinpatientswithParkinson’sdiseaseJoseLBarbozaPharmD,Michae
2、lSOkunMD&BaharakMoshireeMDMSTocitethisarticle:JoseLBarbozaPharmD,MichaelSOkunMD&BaharakMoshireeMDMS(2015)Thetreatmentofgastroparesis,constipationandsmallintestinalbacterialovergrowthsyndromeinpatientswithParkinson’sdisease,ExpertOpiniononPharmacotherapy,16:16,244
3、9-2464,DOI:10.1517/14656566.2015.1086747Tolinktothisarticle:http://dx.doi.org/10.1517/14656566.2015.1086747Publishedonline:16Sep2015.SubmityourarticletothisjournalArticleviews:737ViewrelatedarticlesViewCrossmarkdataFullTerms&Conditionsofaccessandusecanbefoundatht
4、tp://www.tandfonline.com/action/journalInformation?journalCode=ieop20Downloadby:[WenzhouMedicalCollege]Date:06April2017,At:05:23ReviewThetreatmentofgastroparesis,constipationandsmallintestinalbacterialovergrowthsyndromein1.IntroductionpatientswithParkinson’sdisea
5、se2.Prevalenceanddiagnosis3.TreatmentoptionsforJoseLBarboza,MichaelSOkun&BaharakMoshiree?constipation,gastroparesisand?UniversityofMiami-Medicine,Miami,FL,USAsmallintestinalbacterialovergrowthsyndromeIntroduction:Parkinson’sdisease(PD)affectsthenervesoftheentire4
6、.Treatmentofgastroparesisgastrointestinal(GI)tractandmayresultinprofoundgastrointestinal(GI)dysfunctionleadingtopoorpatientoutcomes.CommonGIdisturbancesin5.TreatmentofsmallintestinalbacterialovergrowthpatientswithPDincludegastroparesis(GP),constipationandsmallint
7、estinalsyndromebacterialovergrowthsyndrome(SIBO).Inparticular,GPisdifficulttotreatduetothelimitedoptionsavailableandprecautions,contraindicationsand6.Conclusionadverseeffectsassociatedwiththeapprovedtreatments.Moreover,some7.Expertopinioncommonlyusedmedicationsca
8、nworsenpre-existingPD.Areascovered:OurreviewwillfocusontreatmentoptionsforGPandSIBOwithmotilinagonists,dopaminereceptorantagonists,Ghrelinagonistsmuscarinicago