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《貝那普利聯(lián)合保腎康治療慢性腎小球腎炎的臨床療效分析及其價(jià)值研究.doc》由會(huì)員上傳分享,免費(fèi)在線閱讀,更多相關(guān)內(nèi)容在工程資料-天天文庫(kù)。
1、貝那普利聯(lián)合保腎康治療慢性腎小球腎炎的臨床療效分析及其價(jià)值研究【摘要】目的:探討貝那普利聯(lián)合保腎康治療慢性腎小球腎炎的臨床療效及其價(jià)值。方法:選取2013年12月-2015年12月本院收治的已明確診斷為原發(fā)性慢性腎小球腎炎180例患者作為研究對(duì)象,按照隨機(jī)數(shù)字表法將其分為對(duì)照組92例和觀察組88例o對(duì)照組給予鹽酸貝那普利片口服治療,觀察組給予鹽酸貝那普利片+保腎康聯(lián)合治療,4周為一療程,兩組均連續(xù)治療4個(gè)療程。觀察并比較兩組治療前后血壓、24h尿蛋白定量情況及總有效率。結(jié)果:治療前,對(duì)照組血壓(139+12)/(78±7)mmHg,觀察組(138±11)/(80±9)mmHg,比較差異
2、無(wú)統(tǒng)計(jì)學(xué)意義(P>0.05);治療后,對(duì)照組血壓(136±10)/(76±7)mmHg,觀察組(135±10)/(78±8)mmHg,兩組血壓均較治療前有所降低,但比較差異均無(wú)統(tǒng)計(jì)學(xué)意義(P>0.05),且兩組間比較差異亦無(wú)統(tǒng)計(jì)學(xué)意義(P>0.05)o治療前,對(duì)照組24h尿蛋白定量為(1.87±0.62)g,觀察組24h尿蛋白定量為(1.92±0.67)g,比較差異無(wú)統(tǒng)計(jì)學(xué)意義(P>0.05);治療后,對(duì)照組24h尿蛋白定量為(0.89±0.45)g,觀察組24h尿蛋白定量為(0.61+0.41)g,兩組24h尿蛋白定量均較治療前明顯降低,且治療后觀察組明顯低于對(duì)照組,比較差異均有統(tǒng)計(jì)
3、學(xué)意義(P【關(guān)鍵詞】鹽酸貝那普利片;保腎康;慢性腎小球腎炎;臨床療效;價(jià)值A(chǔ)nalysisandResearchonClinicalEfficacyandValueofBenazeprilCombinedwithPiperazineFerulateTabletsintheTreatmentofChronicGlomerulonephritis/XIEGuang-jie,YIFu-gan.//MedicalInnovationofChina,2016,13(27):049-052【Abstract】Objective:Toexploretheclinicalefficacyandvalu
4、eofBenazeprilcombinedwithPiperazineFerulateTabletsinthetreatmentofchronicglomerulonephritis.Method:FromDecember2013toDecember2015,180casesofclearlydiagnosedtosufferfromprimarychronicglomerulonephritisinourhospitalwereselectedastheresearchobjects,theyweredividedintothecontrolgroupof92casesandtheo
5、bservationgroupof88casesaccordingtotherandomnumbertablemethod.ThecontrolgroupwasgivenoralBenazeprilHydrochlorideTabletstherapyandtheobservationgroupwasgivenBenazeprilHydrochlorideTabletscombinedwithPiperazineFerulateTabletstherapy,4weeksfor1coursesoftreatmentandtwogroupswerecontinuoustreatmentof
6、4courses.Thebloodpressure,24hurineproteinquantitybeforeandaftertreatmentandtotaleffectiverateoftwogroupswereobservedandcompared.Result:Beforetreatment,thebloodpressureinthecontrolgroupwas(139±12)/(78±7)mmHgandthatoftheobservationgroupwas(138±11)/(80±9)mmHg,thedifferencewasnotstatisticallysignifi
7、cant(P>0.05)?Aftertreatment,thebloodpressureinthecontrolgroupwas(136±10)/(76±7)mmHgandthatoftheobservationgroupwas(135+10)/(78±8)mmHg,thebloodpressureintwogroupswaslowerthanbeforetreatment,buttherewasnosignificantdifference,