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1、·臨床研究中國醫(yī)藥導(dǎo)報2013年12月第10卷第35期CT引導(dǎo)下射頻消融術(shù)在實體腫瘤治療中的臨床應(yīng)用金成江蘇省鹽城市第二人民醫(yī)院影像科,江蘇鹽城224003【摘要】目的探討CT引導(dǎo)下射頻消融術(shù)(RFA)在實體腫瘤治療中的臨床效果。方法選擇2009年1月~2012年12月鹽城市第二人民醫(yī)院收治的2l例實體腫瘤患者的臨床資料進(jìn)行分析,其中,周圍型肺癌3例,原發(fā)性肝癌13例,肝癌切除術(shù)后復(fù)發(fā)2例,肝癌介入術(shù)后復(fù)發(fā)2例,肝癌介入術(shù)后腹膜后轉(zhuǎn)移癌1例,所有患者均給了CT引導(dǎo)下RFA治療,觀察患者術(shù)前、術(shù)中血壓、脈搏及血氧飽和度的變化,臨床療
2、效以及并發(fā)癥。結(jié)果21例患者術(shù)中血壓、脈搏及血氧飽和度無明顯變化,與術(shù)前比較,差異尤統(tǒng)計學(xué)意義(P>O.05);總有效率為90.5%;l例出現(xiàn)嘔吐,3例局部疼痛,1例術(shù)后出現(xiàn)胸腔積液,1例肝周有少量滲,經(jīng)對癥治療后好轉(zhuǎn);術(shù)后10個月復(fù)查CT,15例患者腫瘤完全壞死,4例患者腫瘤部分壞死。結(jié)論CT引導(dǎo)下經(jīng)皮穿刺RFA治療實體腫瘤是一種安全、有效的微創(chuàng)治療方法。[關(guān)鍵詞】射頻消融術(shù);CT;實體腫瘤;肝癌;肺癌[中圖分類號]R730.5【文獻(xiàn)標(biāo)識碼]A[文章編號]1673—7210(2013)12(b)一0080一O4Clinicala
3、pplicationofCTguidedpercutaneousradiofrequencyablationinthetreatmentofsolidtumorsJINChengDepartmentofImaging,theSecondPeopleSHospitalofYanchengCity,JiangsuProvince,Yancheng224003,China[Abstract]ObjectiveToexploretheclinicaleffectofCTguidedpercutaneousradiofequencyabla
4、tion(RFA)inthetreatmentofsolidtumors.MethodsTheclinicaldataof21patientswithsolidtumorsintheSecondPeoplesHospitalofYanchengCityfromJanuary2009toDecember2012wereanalyzed,amongthem,3caseswithperipherallungcancer,13caseswithprimarylivercancer.2caseswithrecurrenceljvercanc
5、erafterresection.2caseswithrecurrencehepatocellularcarcinomaafterinter—ventional,1casewithretroperitonealmetastaticcarcinomaafterinterventionalforhepatocellularearcinonla,allpatientsweregivenRFAtherapyunderCTguidance,thechangesofbloodpressure,pulseandbloodoxygensatura
6、tion,clinicalcurativeef-fectandcomplicationspreoperativeandintraoperativewereobserved.ResultsTheintraoperativebloodpressure,pulseandbloodoxygensaturationin21easeshadnoobviouschanges,comparedwithbeforeoperation,therehadnostatisticallysignif-icantdifference(尸>O.O5);thet
7、otaleffectiveratewas90.5%;1c,asewithvomiting,3caseswithlocalpain,1casewithap—pearedpleuraleffusionafteroperation,1casewithliversuroundedbyasmallamountofbleeding,theyallturnedforthebetteraftersymptomatictreatment;recheckedtheCTpostoperative10months,15patientswerecomple
8、tetumornecrosis,4easeswithtumorpartialnecrosis.ConclusionCTguidedpercutaneouspunctureRFAtreatmentofsolidtumorsisasafeandeffe