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《T2WI、DWI 及梯度回波同、反相位成像檢測(cè)乙肝肝硬化背景小肝癌的定量研究-論文.pdf》由會(huì)員上傳分享,免費(fèi)在線閱讀,更多相關(guān)內(nèi)容在行業(yè)資料-天天文庫(kù)。
1、·868·臨床放射學(xué)雜志2014年第33卷第6期腹部放射學(xué)T2WI、DWI及梯度回波同、反相位成像檢測(cè)乙肝肝硬化背景小肝癌的定量研究張學(xué)琴,陸健,王霄英,繆小芬,張濤,梁宏偉,黃愛娜,丁丁,姜吉鋒,方艷,楊雪飛【摘要】目的定量評(píng)估T:wI、擴(kuò)散加權(quán)成像(DWI)、同相位(IP)及反相位(OP)成像對(duì)乙肝肝硬化背景小肝癌(SHCC)的檢測(cè)能力。方法42例乙肝肝硬化患者共46個(gè)經(jīng)病理證實(shí)的SHCC病灶,均行TWI、DWI、IP及OP掃描。分析病灶在4個(gè)序列上的信號(hào)特征,測(cè)量SHCC及肝實(shí)質(zhì)背景在4個(gè)序列上的sI及SD噪聲,比較T,WI、DWI、
2、IP及OP對(duì)乙肝肝硬化背景SHCC的檢出率并定量分析上述4個(gè)序列檢測(cè)SHCC的信號(hào)噪聲比(SNR)及對(duì)比噪聲比(CNR)。結(jié)果T:WI、DWI、IP及OP對(duì)乙肝肝硬化背景SHCC的檢出率差異無(wú)統(tǒng)計(jì)學(xué)意義(P>0.05)。SNR:DWI>IP>OP>T2WI,各組間SNR差異均有統(tǒng)計(jì)學(xué)意義(P<0.05);CNR:DWI>T,WI、IP、OP,DW1分別與TWI、IP、OP比較差異均有統(tǒng)計(jì)學(xué)意義(P<0.05),T2WI、IP、OP3組間差異無(wú)統(tǒng)計(jì)學(xué)意義(P>0.05)。結(jié)論DWI檢測(cè)乙肝肝硬化背景SHCC的SNR和CNR最高,顯著優(yōu)于TWI
3、、IP和OP,但是4個(gè)序列對(duì)SHCC的檢出率并無(wú)顯著差異?!娟P(guān)鍵詞】肝細(xì)胞肝癌肝硬化磁共振成像T2WeightedImaging,DifusionWeightedImaging,GradientRecalledEchoInPhaseandOpposedphaseforQuantitativeDetectionofSmallHepatocellularCarcinomainPatientswithHepatitisBInducedCirrhosis:AComparisonStudyZHANGXueqin,LUJian,WANGXiaoying
4、,eta1.DepartmentofRadiology,theThirdPeoplegHospitalofNantong,JiangsuProvince226006,P.R.China【Abstract】ObjectiveToassessT2weightedimaging(T2wI),Diffusionweightedimaging(DWI),Gradientrecalledecho—Inphase(IP)andOpposedphase(OP)forquantitativedetectionofsmallhepatocellularcarc
5、inomas(SHCC)inpa—tientswithhepatitisBinducedcirrhosis.MethodsAtotalof42hepatitisBinducedcirrhoticpatientswith46SHCCwhichwerepathologicallyconfirmed,underwentT2WI,DWI,IPandOPMRscanning.ThemanifestationsofSHCConthefoursequenceswereanalyzed,thesignalintensity(SI)ofSHCCandlive
6、rparenchymaonthefoursequencesweremeas—ured,thestandarddeviationofnoise(SDnoise),thedetectionrate,SNRandCNRofSHCConT,WI。DWI.IPandOPwerecompared.Results(1)Therewerenostatisticallysignificantdifference(P>0.05)ofdetectionratesamongT2wI,DWI,IPandOP.(2)ForSNR:DWI>IP>OP>T2wI,whic
7、hhadstatisticallysignificantdifference(P<0.05)a—mongT2WI,DWI,IPandOP;ForCNR:DWI>T2WI,IP,OP,whichhadstatisticallysignificantdifferences(P<0.05)betweenDWIandT2wI,IP,OP,respectively,nostatisticallysignificantdifference(P>0.05)couldbedetectedamongT2WI,IPandOP.ConclusionTheSNRa
8、ndCNRwasthehighestonDWIamongalltheaequences.whichwassupe—riortoT2WI,IPandOP,butthedetecti