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1、·ll98·臨床放射學(xué)雜志2014年第33卷第8期腹部放射學(xué)能譜CT估算原發(fā)性肝癌其血供比例的初步研究高永廣，郝敬明，李光超，趙寶忠，師毅冰，王濤，夏萍，陳剛【摘要】目的利用能譜cT(碘基圖)對(duì)肝癌患者及正常人群進(jìn)行測(cè)量，估算不同病變其血供比例，并對(duì)其進(jìn)行分析。方法對(duì)22例原發(fā)性肝癌進(jìn)行分析，20名正常人群作為對(duì)照組，測(cè)得病變動(dòng)脈期及靜脈期碘含量數(shù)值，并得出肝動(dòng)脈期與靜脈期百分比進(jìn)行統(tǒng)計(jì)學(xué)分析，同時(shí)對(duì)肝癌患者依據(jù)Child—Pugh分級(jí)進(jìn)行分組，并與正常人群進(jìn)行方差分析。結(jié)果利用正常肝臟及肝癌血供比例進(jìn)行比較，得出兩組數(shù)據(jù)之
2、間差異具有統(tǒng)計(jì)學(xué)意義(t值=25．34，P<0．05)，正常人群及Child．Pugh分級(jí)對(duì)多組均數(shù)進(jìn)行方差分析(F值=15．58)，Child—Pugh組別較正常人群差異具有統(tǒng)計(jì)學(xué)意義(P值分別為0．007、0．000、0．000)，Child—PughA組較Child．PughB組及C組差異亦具有統(tǒng)計(jì)學(xué)意義(尸值分別為0．008、0．009)，但Child—PughB組與Child—PughC組之間差異無(wú)統(tǒng)計(jì)學(xué)意義(P=0．316)。結(jié)論利用能譜CT測(cè)量其動(dòng)脈期及靜脈期碘含量之比，可以估算出肝癌其血供比例較正常肝組織血供
3、比例發(fā)生改變，從而更簡(jiǎn)便地發(fā)現(xiàn)肝癌其血供比例的改變。【關(guān)鍵詞】能譜肝臟體層攝影術(shù)，x線計(jì)算機(jī)EnergySpectralCTScansforEstimationofHepaticArteryIndexofLiverCancer：APreliminaryStudyGAOYongguang，HAOJingming，LIGuangchao，eta1．DepartmentofRadiology，XuzhouMunicipalCentralHospital，Xuzhou，JiangsuProvince221000，P．R．China【
4、Abstract】ObjectiveToestimatetheproportionofhepaticbloodsupplyinnormalsubjectsandinpatientswithlivercancerbyusingenergyspectralCT(iodinefigure)．MethodsAtotalof22patientswithprimarylivercancer(studygroup)and20healthysubjects(controlgroup)wereenrolledinthisstudy．Theio
5、dinevalueswithinthelesionsinarterialandvenousphaseweredetermined，andthepercentageofbloodflowinhepaticarterialphaseandvenousphasewerethusobtained．Theresultswerestatisticallyanalyzed．AccordingtoChild—Pughcriterion，thepatientsweredividedintodifferentgroups．Theresultsw
6、erecomparedwithnormalpopulationbyusingvarianceanalysis．ResultsStatisticallysignificantdifferencesinthebloodsupplyexistedbetweennormallivertissueandlivercancer(t=25．34，P<0．05)．Varianceanal—ysisshowedthatthebloodsupplyinnormalpopulationwassignificantlydifferentwithCh
7、ild—Pu【ghgroup(P=0．007，P=0．007andP=0．000respectively1．SignificantdiferencesinthebloodsupplyexistedbetweenChild-PughAandChild-PughBaswellasbetweenChild—PughAandChild—Pu【ghC(P=0．008，P=0．009respectively)，whilethedifferencebetweenChild—PughBandChild—PughCwasnotsignific
8、ant(P=0．316)．ConclusionIodinecontentinthetissuewhichismeasuredbyenergyspectralCTcanestimatethebloodsupplyinthetissue．Thistechniquecanestimatetheb
