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1、左旋布比卡因與羅哌卡因臂叢神經(jīng)阻滯的對(duì)比研究2008年5月第4
2、6卷第14期左旋布比卡因與羅哌卡因臂叢神經(jīng)阻滯的對(duì)比研究李斌張潔(鄭州大學(xué)第一附屬醫(yī)院麻醉科,鄭州450052)?論著?【摘要】目的比較O.375%左旋布比卡因與O.375%羅哌卡因用于臂叢神經(jīng)阻滯的臨床效果.方法5O例ASAI～I(xiàn)I級(jí)行擇期上肢手術(shù)患者,隨機(jī)分為左旋布比卡因組(L組),羅哌卡因組(R組),各25例.分別用O.375%左旋布比卡因和0.375%羅哌卡因30mL行肌問溝臂叢神經(jīng)阻滯.監(jiān)測并記錄麻醉前(Tn),麻醉后即刻(T),麻醉后5min(T2),10min(T3).20min
3、(T4),30min()的HR,MAP,SpO,RR,觀察兩組的麻醉起效時(shí)間,術(shù)后感覺及運(yùn)動(dòng)功能恢復(fù)時(shí)間和麻醉鎮(zhèn)痛質(zhì)量.結(jié)果兩組在各時(shí)間段的HR,MAP,SpO2,RR差異無統(tǒng)計(jì)學(xué)意義.麻醉起效時(shí)間:L組為(4.6±1.2)rain,R組為(4.9±1.4)min(P>0.05);感覺和運(yùn)動(dòng)功能恢復(fù)時(shí)間:L組為(485±140)minVS(220±30)min,R組為(445±130)minvs(186±38)min(P>0.05o兩組麻醉鎮(zhèn)痛質(zhì)量相似,差異無統(tǒng)計(jì)學(xué)意義.結(jié)論0.375%左旋布比卡因與0.375%羅哌卡因30mL皆可用于臂叢神經(jīng)
4、阻滯,兩者麻醉起效時(shí)間,神經(jīng)功能恢復(fù)時(shí)間及麻醉鎮(zhèn)痛質(zhì)量相似.【關(guān)鍵詞】左旋布比卡因;羅哌卡因;臂叢神經(jīng)阻滯;麻醉;l臨床效果【中圖分類號(hào)1R614.4【文獻(xiàn)標(biāo)識(shí)碼】A【文章編號(hào)】1673—9701(2008)14—21—03AComparativeStudyofBranchialPlexusBlockwithLevobupivacaineandRopivocainel矗B.m_ANGJ/eDepartmentofAnesthesiology,TheFirstAffiliatedHospitalofZhengzhouUnivercity,Zhengzhou4
5、50052【Abstract1ObjectiveTocomparetheclinicalefficacyof0.375%levopubivacaineandropivacaineusedinbrachialplexusblock.MethodsFiftyASAI-IIpatientsundergoingupperlimbesoperationunderbrachialplexusblockwererandomlydividedintotwogroups,groupL(n=25)andgroupR(n=25).Patientsreceivedintersea
6、lenebrachialplexusblockwith0.375%Lor0.375%R30mL.HR,MAP,SpO2,RRduringoperationwererecorded.Theonsettime,thetimetorecoveryofsensoryandmotorfunctionandtheefficacyofanesthesiawereobserved.ResultsTherewasnosignificantdifferencebetweengroupLandgroupRinHR,MAP,Sp02,RRduringoperation.Theon
7、settimeofsurgicalanesthesiaWaS(4.6±1.2)minWithlevopivacaineand(4.9±1.4)minWithropivacaine(P>0.05).ThetimetorecoveryofsensoryandmotorfunctionWaS(485±140)minVS(220±30)miningroupLand(445±130)minVS(186±38)miningroupR,respectively(P>O.05).BothgroupLandgroupRcouldprovidethesimilar
8、efficacyofanalgesia.ConclusionBoth0.375%levobupivacaineandropivocaineusedinbraehialplexusblockCanprovidecomparablesurgicalanesthesia.【KeyWords】Levobupicaine;Ropivacaine;Brachialplexusblock;Anesthesia;Clinicalefficacy臂叢神經(jīng)阻滯是骨科上肢手術(shù)常用的麻醉方法.左旋布比卡因?yàn)椴急瓤ㄒ虻淖笮悩?gòu)體,是l臨床上一種新型局麻藥,有研究表明【1]在藥效及藥
9、代動(dòng)力學(xué)方面與羅哌卡因相似.本試驗(yàn)采用相同濃度的左旋布比卡因與羅哌
