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《中藥聯(lián)合玻璃體腔內(nèi)注射曲安奈德治療糖尿病性黃斑水腫的療效觀察》由會(huì)員上傳分享,免費(fèi)在線閱讀,更多相關(guān)內(nèi)容在應(yīng)用文檔-天天文庫(kù)。
1、中藥聯(lián)合玻璃體腔內(nèi)注射曲安奈德治療糖尿病性黃斑水腫的療效觀察武漢市屮西醫(yī)結(jié)合醫(yī)院湖北武漢430022目的觀察益氣活血利水方聯(lián)合玻璃體腔內(nèi)注射曲安奈德治療糖鉍病性黃斑水腫的臨床療效。方法將58例(58眼)糖鉍病性黃斑水腫患者隨機(jī)分為對(duì)照組和屮西醫(yī)結(jié)合治療組,每組29例。對(duì)照組給予玻璃體腔內(nèi)注射曲安奈德,每月1次,連續(xù)3個(gè)月,屮西醫(yī)結(jié)合治療組在對(duì)照組治療基礎(chǔ)上加用自擬益氣活血利水方,每口2次,療程均為3個(gè)月,觀察治療前后患者最佳矯正視力(BCVA)、黃斑屮心凹厚度(CMT)。結(jié)果治療后各時(shí)間點(diǎn)兩組BCVA及CMT的改善程度均較治療前顯著好轉(zhuǎn)(均P&
2、lt;0.05),但至治療后6m對(duì)照組BCVA呈現(xiàn)下降趨勢(shì),CMT呈現(xiàn)上升趨勢(shì),而屮西醫(yī)結(jié)合治療組療效保持平穩(wěn),治療后3m及6m兩組間差異有統(tǒng)計(jì)學(xué)意義(P<0.05),治療后6m對(duì)照組病例有效率為68.4%,屮西醫(yī)結(jié)合治療組有效率為86.8%,兩組間比較差異有統(tǒng)計(jì)學(xué)意義(P<0.05)o結(jié)論采用自擬益氣活血利水方聯(lián)合玻璃體腔內(nèi)注射曲安奈德治療糖尿病性黃斑水腫可有效減輕視網(wǎng)膜滲漏及黃斑水腫,更能穩(wěn)定現(xiàn)存視力,延遲復(fù)發(fā)時(shí)間?!娟P(guān)鍵詞】屮藥;曲安奈德;糖鉍病性黃斑水腫Intravitrealtriamcinoloneacetonidein
3、jectioncombiningwithtraditionalChinesemedicineinTreatmentofdiabeticmacularedemaWuChaoqiong,ZhuJing(DepartmentofOphthalmology,theintegratedTCM-WesternmedicineHospitalofWuhanCity,Wuhan430022,China)Abstract:ObjectiveToinvestigatetheclinicalefficacyofintravitrealinjectionoftriam
4、cinoloneacetonidecombinedwithtraditionalChinesemedicineintreatmentofdiabeticmacularedema.MethodsThe58patients(58eyes)withdiabeticmacularedemawererandomlydividedintotwogroups(treatmentgroupandcontrolgroup).Thecontrolgroup(n=29)wastreatedwithintravitrealinjectionoftriamcinolon
5、eacetonide,andthetreatmentgroup(n=29)underwentintravitrealinjectionoftriamcinoloneacetonidecombinedwithtraditionalChinesemedicine.Theresultsweregeneralanalyzedbythebestcorrectedvisualacuity(BCVA),opticalcoherencetomography(OCT)beforeand1,3,6monthsaftertreatment.Result:Thedif
6、ferentcesofBCVAandCMTvaluesofthetwogroupsweresignificantlyineachtimeperiodbeforeandaftertreatmentCallP<O.O5),buttheBCVApresenteddowntrendandtheCMTpresenteduptrendinthecontrolgroupafter6moftreatment,whileweresatisfactoryandsteadyinthetreatmentgroup.Therewasstatisticallysig
7、nificantdifferencebetweenthetwogroupsafter6moftreatment,(P<0.05).Totreat6mfollowup,theeffectiveratewas68.4%inthecontrolgroup,andtheeffectiverateoftreatmentgroupwas86.8%,therewasstatisticallysignificantdifferencebetweenthetwogroups(P<0.05).Conclusion:Intravitrealinjecti
8、onoftriamcinoloneacetonidecombinedwithtraditionalChinesemedicineintreatment