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《準(zhǔn)分子激光角膜屈光術(shù)后皮質(zhì)類固醇性高眼壓臨床相關(guān)因素分析_論文》由會(huì)員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在學(xué)術(shù)論文-天天文庫(kù)。
1、準(zhǔn)分子激光角膜屈光術(shù)后皮質(zhì)類固醇性高眼壓臨床相關(guān)因素分析作者：王秀青 翟軍印 賀翔鴿 白繼【摘要】 目的：探討準(zhǔn)分子激光角膜屈光術(shù)后皮質(zhì)類固醇性高眼壓的發(fā)生率、臨床相關(guān)因素及預(yù)后。方法：對(duì)2017-12/2017-12間行LASIK或LASEK的2060例4060眼滴糖皮質(zhì)激素眼液（1g/L地塞米松及1g/L氟米龍）2～3mo，術(shù)后1wk；1，2，3，6mo及1a觀察眼壓變化，對(duì)高眼壓者進(jìn)行治療，并采用Logistic方法分析高眼壓與年齡、性別、眼別、最大徑線屈光度、最大徑線角膜曲率、角膜切削深度和眼底垂直徑杯/
2、盤比值的相關(guān)性。結(jié)果：有88例143眼發(fā)生了高眼壓，發(fā)生率為%，所有高眼壓患者經(jīng)藥物治療眼壓均降至正常。Logistic回歸分析結(jié)果顯示，眼底杯/盤比值與高眼壓相關(guān)性P值為，OR值為，其他因素P值均大于。眼底垂直徑杯/盤比值大于等于者發(fā)生皮質(zhì)類固醇性高眼壓的幾率是小于者的倍。結(jié)論：準(zhǔn)分子激光角膜屈光術(shù)后應(yīng)用糖皮質(zhì)激素眼液可引起部分患者發(fā)生皮質(zhì)類固醇性高眼壓，眼底垂直徑杯/盤比值與皮質(zhì)類固醇性高眼壓有較強(qiáng)相關(guān)性，大于等于是皮質(zhì)類固醇性高眼壓的高危因素，對(duì)眼底杯/盤比值大于等于者術(shù)后可酌情減少激素用量和/或加用降眼壓藥
3、物。11/11【關(guān)鍵詞】皮質(zhì)類固醇性高眼壓 準(zhǔn)分子激光角膜屈光手術(shù) 杯/盤比值Clinicalanalysisofcorticosteroid-inducedocularhypertensionafterlaserkeratorefractivesurgeryAbstractAIM:Tostudytheincidence,clinicalrelatedfactorsandtherapeuticeffectsofcorticosteroid-inducedocularhypertensionafterlaserker
4、atorefractivesurgery(LASIKandLASEK).METHODS:Afollow-upstudyon4060eyesafterlaserkeratorefractivesurgerybetweenDecember2017andDecember2017wasperformed.Corticosteroid(1g/Ldexamethasoneand1g/Lfluoromethalone)eyedropswereapplied2-3monthspost-operativelyandintraocul
5、arpressurewasmeasuredat1week,1,2,3,6and12months,theeyeswithincreaseofintraocularpressureweretreated.Binarylogisticregressionwasusedtoanalyzetherelationshipbetweenocularhypertensionandage,sex,eye,maximumdiopter,maximumcurvature,corneacuttingdepth,andverticalcup
6、/disc:Corticosteroid-inducedocular11/11hypertensionoccurredin%ofthe4060eyes.Theintraocularpressure(IOP)oftheeyesdroppedtonormallevelinallpatientsafterdrugtreatments.Resultsofbinarylogisticregressionshowedsignificance(Pvalue)betweenocularhypertensionandcup/disc
7、ratiowasandallothersexceeded,ORratio:,whichmeanthatincidenceofcorticosteroid-inducedocularhypertensiononpatientswithverticalcup/discratioexceedingwasmore3timesthanthosewithcup/discratiolessthanCONCLUSION:Topicalapplicationofcorticosteroiddropsmaycausecorticost
8、eroid-inducedhypertensioninsomebodyafterlaserkeratorefractivesurgery.Thereisclosecorrelationbetweencorticosteroid-inducedhypertensionandverticalcup/discratio.Cup/discratioexceeding
