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1、ReviewofintestinalhelminthsAscarislumbricoides(roundworm)似蚓蛔線蟲（蛔蟲）Trichuristrichiura(whipworm)毛首鞭形線蟲（鞭蟲）Enterobiusvermicularis(pinworm)蠕形住腸線蟲（蟯蟲）AncylostomaduodenaleNecatoramericanus(hookworms)鉤蟲Trichinellaspiralis旋毛形線蟲Tissue-blooddwellingnematodes--Filaria
2、絲蟲Wuchereriabancrofti班氏吳策線蟲Onchocercavolvulus旋盤尾絲蟲ThehistoryofTrichinellaspiralisInyear1835，YoungJimPaget,afirstyearmedicalstudentatLondonHospitalMedicalSchool,rushedintotheautopsyroom.The51yr-oldItalianbricklayerwhohaddiedoftuberculosis,andthattheywerenowd
3、issecting,alsohad"sandydiaphragm,"aconditionthatdulledeventhesharpestofscalpels.Well,anyway,whentheyhadallclearedtheroom,Jimquietlystolebackinandremovedasmallbitofmuscletissuefromthediaphragm.Hewasmorethancuriousastothenatureof"sandydiaphragm".Hefirstexamin
4、editwithhistrustyhandlenshecarriedforjustsuchasituation.Hethoughthesawsmallwormscoiledupinsideeachnodule.Uponevenhighermagnification,thepresenceofcoiledwormswasrevealed.(Fromwww.trichinella.org)TrichinellaspiralisJimPagetWormsinthe“sandydiaphragm”Trichinell
5、aspiralisTrichinawormswereobservedinporkin1846byJosephLeidy.Hesavedhundredsoflivesbyrecommendingcookingporkatahighenoughtemperaturetokilltheorganism.Lifecycleworkoutin1850’sByRudolphVirchow.TrichinellacontrolRudolfVirchow(Germany)suggestedmandatorydiagnosis
6、ofallmeatattheslaughterhousesin1877?ThishasgreatlyreducedtrichinellosisashumanhealthProblem.WorldwideDistributionParasiticzoonosisFoodborneparasitosisTrichinellaspiralis-cause旋毛蟲病trichinosis,trichiniasis,ortrichinelliasisDistributionofTrichinellaspiralisTri
7、chinosisismostcommonintemperateandarcticclimates-highprevalenceinpork-eatingareasoftheworld.arctictemperateAdultsofTrichinellaspiralisAdults:small,1.5~4mmLarva:femalesgivebirthtolarva(Eggs:hatchinuterus子宮)stichosomeHatchedLarva桿狀體成蟲形態(tài)在診斷上無意義！特點：直接產(chǎn)幼蟲Encyste
8、dlarva幼蟲囊包--infectivestage0.25~0.5mm×0.21~0.42mmLemonshape1~2larvainthecystLifecycleAdultfemaleinmucosaofsmallintestineTrichinacystsinskeletalmuscle骨骼肌Pathogenisis3stages：1.Invasion–1weekfirstsymptomsa
