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1、癥狀性顱內(nèi)動(dòng)脈狹窄行支架治療療效分析及研究摘要:口的探究對(duì)癥狀性顱內(nèi)動(dòng)脈粥樣硬化性狹窄低灌注患者治療屮,顱內(nèi)支架置入能否使患者獲得較好的臨床獲益與風(fēng)險(xiǎn)比。方法回顧性分析2010年2月?2013年11月41例缺血性卒中患者(經(jīng)腦血管造影顯示IAS)患者資料。將患者分為支架組(行顱內(nèi)支架置入術(shù))、藥物組,觀察患者圍手術(shù)期、隨訪期間主要終點(diǎn)事件。結(jié)果手術(shù)成功率100%,圍手術(shù)期大的并發(fā)癥1例?;颊咂骄S訪11.2個(gè)月,12月吋對(duì)比NIHSS評(píng)分好轉(zhuǎn)情況,支架組22例患者,1例術(shù)后并發(fā)腦梗死后,遺留后遺癥,并發(fā)癥發(fā)生率4.5%,12月隨訪時(shí)NIHSS評(píng)分較術(shù)
2、前增加3分,余21例患者12月隨訪時(shí)平均NIHSS評(píng)分下降5.4分。一藥物治療組患者12月隨訪,卒屮復(fù)發(fā)率10.5%,1例出院后4月發(fā)生再次卒中,12月時(shí)NIHSS評(píng)分增加4分,1例患者出院8刀后再次卒中,12月WNIHSS評(píng)分增加5分,余17例患者12月隨訪時(shí)平均NIHSS評(píng)分下降3.8分。具有低灌注特征的顱內(nèi)置入支架患者更能較好的臨床獲益。結(jié)論對(duì)灌注低的癥狀性MS患者,行顱內(nèi)支架置入,患者可能獲益更多。關(guān)鍵詞:癥狀性顱內(nèi)動(dòng)脈狹窄;低灌注;顱內(nèi)支架置入;腦梗死Symptomaticintracranialarterystenosisstenttre
3、atmentforcurativeeffectanalysisandresearchAbstract:ObjectiveToevaluateintracranialstentonwhetherlowperfusionofsymptomaticIASgreaterbenefit/riskratio.MethodsthepatientsfromJanuaryto2012Decemberon2010inintnicranialstentingretrospectively.Thepatientsweredividedintostentgroup>drugg
4、roup,Observedpatientswithprimaryendpointeventsduringtheperioperativeandfollow-up.Resultsthesuccessfulrateofoperationwas100%,perioperativecomplicationsduringoperationin1cases?Thepatientswerefollowedupforanaverageof11.2months,DecembercomparedwithNIHSSscoreimprovement,22patientsco
5、mplicatedwithcerebralinfarctionstentgroup,1casesofpostoperative,bequeathsequela,thecomplicationratewas4.5%,inDecemberthefollow-upwhencomparedwithpreoperativeNIHSSscoreincreasedby3points,morethan21casesofpatientswithfollow-up,themeanNIHSSscoreinDecemberdropped5.4points?Thedrugth
6、erapygrouppatientswerefollowedupinDecember,strokerecurrenceratewas10.5%,1casesoccurredinAprilagainafterdischargestroke,inDecembertheNIHSSscoreincreased4inAugust,1dischargedpatientsafterstroke,inDecembertheNIHSSscoreincreased5inDecember,morethan17patientswerefollowedupaverageNIH
7、SSscoredecreased3.8points.Thathasalowperfusionfeaturesinpatientswithintracranialimplantationcanbenefit.Conclusion:implantationforpatientswithsymptomaticintracranialarterialstenosisofintracranialstentonperfusiondecreasemaybenefitmore?Keywords:symptomaticintracranialarterystenosi
8、s;lowperfusion;intracranialstenting;cerebralinfarction