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1、人連醫(yī)科人學(xué)碩士學(xué)位論文結(jié)腸黑變病158例臨床回顧性分析姓名:劉俊鵬中請學(xué)位級別:碩士專業(yè):內(nèi)科學(xué)指導(dǎo)教師:宮愛霞201106OO碩士生姓名:劉俊鵬指導(dǎo)教師:宮愛霞教授專業(yè)名稱:內(nèi)科學(xué)SI的£擱襯刪黑巫嫌OliilanosiscoliMC)發(fā)病特點,以及MC與年齡、性別、結(jié)腸息肉、結(jié)腸癌的關(guān)系。方法:對2007年7月至2011年4月經(jīng)電子結(jié)腸鏡檢査出158例MC患者,紀(jì)錄每僮臓制崖療胸麻聽狀,血罐傾債處,帶時并慟曙懸杏過瀉藥及服用瀉劑名稱?統(tǒng)訊財各腹聲性娜毬啓厳部魅胖魏鼬部飾壻無癌變等進(jìn)紳@1頗翊新。結(jié)果:MC檢出率為2.68%,女性檢出率明顯高于男性的檢岀率t
2、Jl.im的[酚刖]船,UIK迦DO勸越她發(fā)病舗齡期區(qū)佃軸性年齡(58.99±14.194參酚S0的士働0懐他<0抽胡女W孩繼鮒柱易股型眥(酸纟鹿慶病年齡組較男性偏低;60歲以上檢出率高于60歲以下組(PV0.05)顯示老年人群較中青年更易孩生鈿備腸黑廉?部儉宏笏發(fā)幽蚯結(jié)瞰滿翱虺半細(xì)貂臨貽站腸發(fā)病率較低;本MC組息肉發(fā)病率高于對照組(30.3%VS20?6%,P<0.05);本研究MC組158例患者中檢出癌變5例,檢出率為3.2%,而對照組檢出癌變4例,檢出率為2.3%,MC組與對照組癌變率之間并無統(tǒng)計學(xué)意義(P>0.05)。結(jié)論:1.MC的發(fā)生于年齡、性別密切
3、相關(guān),發(fā)病率隨著年齡的增長呈上升趨勢,多為彥帑人翻別t病"女性IMC憑瞪明猊鉀I男幽怕纜樓憩病癢馳!勢椎偏低o2.MC息肉檢岀率要高于非MC患者。3.結(jié)腸黑變病并未增加結(jié)腸癌發(fā)病率,可能與息肉的早期發(fā)現(xiàn)和早期治療有關(guān)??躺暇w腸黑變病病病困肉息肉囤顧性分析Retrospectiveanalysisofmelanosissoli:areportof158casesBW&sterf^fgreecandidate:LiuJun評pngSupervisor:ProfessorGongEMxiaMajK>rjKRRdftBRMedicineBSB&tractObjecti
4、ve:Toinvestigatethecauseandf^g^genesisofmelanosiscoliaswellasits麗祁淅瓜儷坯林,sex,colorectalpolypusand拓rectalB8ftcer.Methods:TheclinicaldataofOnehundredandwithmelanosiscolidiagnosedbyendoscopyexaminationfromJuly2007KoApril2011wasanalyedonage,sex,historyofconstipation,Laxativesuse,melanosis
5、,withpolypusportorcancerretrospectively.Results:ThedetectionraRRaftMCpatientswasRRfi蘭魏ThedetectionrateBRMCinmalepatientswas0.93%,less0iB8ftWSioffemalepatients(L75%).The電Rneanage、RRRRR.R%RKfiR-was(65.87±11.301),olderthanwomeifs(5&9飪i4.194).FemakMCpatientswereRRRRyoungerthanmaleandshow
6、rfiller酈稠^Ry.Theincidenceofmelanosisinpatientsof60yearsorelderwassignificantlyhigherthanthatofRRR無翻KPg°5),MostofMCwasinvolvedinthewholelargeKfl甩TheincidenceofmelanosisinrighthemicolonwasReBB由anlefthemicolon.怨冊diision:刖iBOfinosiscoliiscloselyrelatedwithageandgender.Then^^lenceofmelano
7、siscoliinapopulationtendstoincreasewithage.Thedetectionrateoffemalesismuchhigherthanmales.FemaleMCpatientsareyoungerHiaMmale.2.ThedetectionrateofMCpatientswithpolypsishigherthanthatofno-MCpatients3.Melanosiscoliseemstohavecorelationshipwithcolonneoplasm.Thereasonisthatcolonpolypsmayb
8、eenfoundandt