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1、·670·張佩斯,等立體定向扣帶回毀損術(shù)治療晚期癌痛[23]Lukaszewicz-ZajacM,MroczkoB,KozlowskiM,etal.ComparaimportantpredictorsofsurvivalafterpancreaticoduodenectomyfortiveevaluationofserumC-reactiveprotein(CRP)levelsinthepancreaticductaladenocarcinoma[J].JOP,2012,13(2):199-differenthistologicalsubtypesofesophagealca
2、ncer(squamous204.cellcarcinomaandadenocarcinomaofesophagus)[J].JClinLab[25]ShimuraT,KitagawaM,YamadaT,etal.C-reactiveproteinisaAnal,2012,26(2):73-81.potentialprognosticfactorformetastaticgastriccancer[J].Anti[24]SanjayP,deFigueiredoRS,LeaverH,etal.PreoperativeserumCcancerRes,2012,32(2):491-
3、496.-reactiveproteinlevelsandpost-operativelymphnoderatioare(編校:談靜)立體定向扣帶回毀損術(shù)治療晚期癌痛張佩斯,劉會,王天成CancerpaintreatedbystereotacticcingulatecortexdamagedZhangPeisi,LiuHui,WangTianchengDepartmentofNeurosurgery,LiaoningProvincePeople'sHospital,LiaoningShenyang110016,China.【Abstract】Objective:Toexplor
4、etheeffectofcingulatecortexdamagesurgerytreatmentoncancerpain.Methods:Of39cases,including20casesoflungcancer,8livercancer,6casesofprostatecancerbonemetastases,bonetumorsin5cases.Usingvisualanalogpainscale(VAS)andMcGillpainquestionnairescale(MPQ)toobservepainscore.Results:Postoperativepainin
5、patientsdisappeared.Stableanalgesiceffectinpostoperative3months,VASscoreMPQscorewassignificantlylowercomparedwithpreoperative(P<0.05)orless,noseriouscomplications,35caseswithdepressionanxietysymptomswereimprovedmarkedly.Conclusion:Bilateralacgdamagedjointiseffectivetreatmentforadvancedcance
6、rpian.【Keywords】cancerpain;cingulategyrusdamaged;depression;anxietyModernOncology2014,22(03):0670-0672【摘要】目的:探索扣帶回毀損術(shù)治療晚期癌痛的效果。方法:選擇應用三階梯治療無效的晚期癌痛病人39例,包括肺癌20例,肝癌骨轉(zhuǎn)移8例,前列腺癌骨轉(zhuǎn)移6例,骨腫瘤患者5例,其中35例伴抑郁癥及焦慮癥。采用直觀模擬疼痛量表(VAS)和McGill疼痛問卷量表(MPQ)分別在術(shù)前和書后進行疼痛評分,同時記錄手術(shù)前后患者使用止痛藥的種類和最大劑量,將術(shù)后3個月的VAS、MPQ評分與術(shù)前評
7、分進行比較。結(jié)果:術(shù)后患者癌痛基本消失,只需服用小劑量止痛藥物。術(shù)后3個月止痛效果穩(wěn)定,VAS評分及MPQ評分較術(shù)前明顯降低(P<0.05),無嚴重并發(fā)癥發(fā)生,其中35例患者的抑郁癥及焦慮癥明顯好轉(zhuǎn)。結(jié)論:雙側(cè)扣帶回前部聯(lián)合毀損術(shù)能有效治療晚期癌痛,緩解患者的抑郁癥及焦慮癥。【關(guān)鍵詞】晚期癌痛;扣帶回毀損;抑郁癥;焦慮癥【中圖分類號】R730.5【文獻標識碼】ADOI:10.3969/j.issn.1672-4992.2014.03.58【文章編號】1672-4992-(2014)03-06