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1、女性冠心病臨床特征與冠狀動(dòng)脈病變特點(diǎn)分析【摘要】目的探討女性冠心病的臨床特征與冠狀動(dòng)脈病變特點(diǎn)，以提高診治水平。方法以男性為對(duì)照，回顧性分析246例女性冠心病患者的臨床資料及冠狀動(dòng)脈造影結(jié)杲。結(jié)果女性冠心病發(fā)病年齡較男性晚(PvO.05);絕經(jīng)為女性冠心病的特殊危險(xiǎn)因素，絕經(jīng)后雌二醇水平降低，脂質(zhì)代謝紊亂加重;高血床、高血脂、肥胖及糖尿病是女性冠心病的重要危險(xiǎn)因素，有高血壓、糖尿病、肥胖者顯著高于男性(PvO.05);女性吸煙者顯著低于男性(P<0.05)o女性不典型心絞痛及非特異性ST-T改變多于男性;女性急性非ST段抬高型心肌梗死顯著高于男性，而急性ST段抬高型心肌梗死顯著低于
2、男性(PvO.05)。女性冠狀動(dòng)脈病變以單支病變多見(jiàn)，左前降支最易受累，女性多支病變多于男性(P<0.05)o女性選擇性介入治療明顯少于男性(PvO.05)。結(jié)論女性冠心病具有獨(dú)特的臨床特征及冠狀動(dòng)脈病變特點(diǎn)，應(yīng)加強(qiáng)對(duì)女性冠心病防治的研究?！娟P(guān)鍵詞】女性;冠心病;臨床特征;冠狀動(dòng)脈造影［Abstract］ObjectiveToinvestigatetheclinicalcharacteristicsofcoronaryheartdiseaseandfeaturesofcoronaryarterylesionsinfemalepatientswithcoronaryheartdise
3、ase(CHD)inordertoenhancethediagnosticandtherapeuticlevels.MethodsTheclinicaldateandresultsofselectedcoronaryangiographyin246femalepatientswithCHDwereretrospectivelyanalyzed,and358malepatientswithCHDwereservedasthecontrols.ResultsTheageoffemalepatientswithCHDwassignificantlyolderthanthatofmales
4、(P<0.05),andmenopausewasspecialriskfactorforfemalepatientswithCHD,Thedecreaseofestradiolaftermenopause,aggratatedlipidmetabolicdisorder,hypertention,hyperlipidemia,obesityanddiabetesmellitusweremajorriskfactorsinfemalepatientswithCHD.Theincidencesofdiabetes,hyperlipidemiaandobesityinfemalepati
5、entswithCHDweresignificantlyhigherthanthoseinmales(P<0.05),however,thenumberoffemaleofsmokingwassignificantlylowerthanthatofmales(P<0.05).Theatypicalanginapectorisandnon-specificityST-Tchangesinfemalepatientsweremuchmorethanthoseofmales,andtheincidenceofacuteNSTEMIinfemalepatientswassignifican
6、tlyhigherthanthatinmales,however,theincidenceofacuteSTEMIwassignificantlylowerthanthatinfemales(P<0.05).ThesinglevessellocalizedstenosisinLADwastypicallesionsinfemalepatients,andmultiple-vessellesioninfemaleswasmuchmorethanthatinmales(P<0.05).ThefemalepatientswhochosePCIwereobviouslylessthanma
7、lepatients(P<0.05).ConclusionTherearespecialclinicalcharacteristicsandfeaturesofcoronaryailerylesionsinfemalepatientswithCHD,sothestudyonthepreventionandtreatmentforCHDinfemalepatientsshouldbeenhanced?【Keywords］female;coronaryheartdisea
