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《普萘洛爾凝膠治療嬰幼兒血管瘤的臨床療效與安全性分析》由會員上傳分享，免費在線閱讀，更多相關(guān)內(nèi)容在學(xué)術(shù)論文-天天文庫。
1、-------福建醫(yī)科大學(xué)2009級碩士學(xué)位論文效差異無統(tǒng)計學(xué)意義（P>0.05）。隨訪過程中患兒未出現(xiàn)明顯心率、血壓下降和空腹血糖降低，無飲食、睡眠不良情況，血常規(guī)、血生化檢驗，心電圖及心臟彩超檢查未出現(xiàn)明顯異常。結(jié)論：普萘洛爾凝膠治療嬰幼兒血管瘤療效較好，尤其是對于淺表型血管瘤，能達到口服普萘洛爾治療的相同效果，且不良反應(yīng)少，為臨床提供了一種非侵入性的、安全方便的、患兒較易接受的治療新途徑。關(guān)鍵詞：嬰幼兒血管瘤普萘洛爾凝膠4-----------萬方數(shù)據(jù)-----------福建醫(yī)科大學(xué)2009級碩士學(xué)位論文ClinicalObservationandtheSa
2、fetyAnalysisofPropranololGelonInfantileHemangiomasAbstractObjective:TheobjectiveofthisstudyistoevaluatetheefficacyandsecurityofPropranololGelintreatmentofinfantilehemangiomaindifferenttypesandlocation.ItisexpectedtoprovideatheoreticalbasisoftherolePropranololGelplayedininfantilehemangi
3、omaforitsclinicuse.Methods:PropranololGelwasappliedto51infantswithheamngiomaswhoareinlinewiththeinclusioncriteriaofthetreatment.Twenty-twoweremale,andtwenty-ninewerefemale.Theageoftheinfantswere28daysto12monthsoldwithameanageof3.8months.Theheamngiomas’areawere5×5～78×18mm.Superficialhem
4、angiomawere28,deephemangiomawere6andmixedhemangiomawere17.Thehemangiomalocatedinheadandneckwere32,intrunkwere10,andextremitieswere9.Weexcludedthecontraindicationsoftreatmentandgainedtheconsentoffamilymenbersagreementandsignedconsent.Theinfantswasappliedtopropranololgelthreetimesperday.
5、Evaluatetheefficacyofthegelbyobsevedthesize,thecolour,thePSVandRI.EvaluatethesecurityofthegelbyobsevedECG,UCG,BloodBiochemicalCompleteSetetalandtheinfants'Bloodpressure,heartrate,fastingbloodsugaranddiet,sleepandothergeneralsituation.TheresultswereevaluatedusingAchauersystem．Results:8i
6、n51infantswereappliedtreatmentfor2month,12were5months,17were7months,14were9monthsinfants.Hemangiomasofchildrenareall5-----------萬方數(shù)據(jù)-----------福建醫(yī)科大學(xué)2009級碩士學(xué)位論文stopgrowthwiththesizeissmaller,textureismoresoftaftertreatment.PSVislowerandRIisincreasein25cases(P<0.05).Theoverallresponsewa
7、sscaleI(poor)in4patient(7.84%),scaleII(moderate)in18patients(35.29%),scaleШ(good)in22patients(43.14%)andscaleIV(excellent)in7patients(13.73%).Thechangesinsuperficialhemangiomawasbetterthanothers(P<0.05).Thereisnosignificantdifferentinlocated(P>0.05).Childreninthefollow-upprocessdoesn
