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1、福建醫(yī)科大學2009級碩士學位論文效差異無統(tǒng)計學意義(P>0.05)。隨訪過程中患兒未出現(xiàn)明顯心率、血壓下降和空腹血糖降低,無飲食、睡眠不良情況,血常規(guī)、血生化檢驗,心電圖及心臟彩超檢查未出現(xiàn)明顯異常。結(jié)論:普萘洛爾凝膠治療嬰幼兒血管瘤療效較好,尤其是對于淺表型血管瘤,能達到口服普萘洛爾治療的相同效果,且不良反應(yīng)少,為臨床提供了一種非侵入性的、安全方便的、患兒較易接受的治療新途徑。關(guān)鍵詞:嬰幼兒血管瘤普萘洛爾凝膠4萬方數(shù)據(jù)福建醫(yī)科大學2009級碩士學位論文ClinicalObservationandtheSafetyAnalysisofPropranololGelonInfantile
2、HemangiomasAbstractObjective:TheobjectiveofthisstudyistoevaluatetheefficacyandsecurityofPropranololGelintreatmentofinfantilehemangiomaindifferenttypesandlocation.ItisexpectedtoprovideatheoreticalbasisoftherolePropranololGelplayedininfantilehemangiomaforitsclinicuse.Methods:PropranololGelwasappli
3、edto51infantswithheamngiomaswhoareinlinewiththeinclusioncriteriaofthetreatment.Twenty-twoweremale,andtwenty-ninewerefemale.Theageoftheinfantswere28daysto12monthsoldwithameanageof3.8months.Theheamngiomas’areawere5×5~78×18mm.Superficialhemangiomawere28,deephemangiomawere6andmixedhemangiomawere17.T
4、hehemangiomalocatedinheadandneckwere32,intrunkwere10,andextremitieswere9.Weexcludedthecontraindicationsoftreatmentandgainedtheconsentoffamilymenbersagreementandsignedconsent.Theinfantswasappliedtopropranololgelthreetimesperday.Evaluatetheefficacyofthegelbyobsevedthesize,thecolour,thePSVandRI.Eva
5、luatethesecurityofthegelbyobsevedECG,UCG,BloodBiochemicalCompleteSetetalandtheinfants'Bloodpressure,heartrate,fastingbloodsugaranddiet,sleepandothergeneralsituation.TheresultswereevaluatedusingAchauersystem.Results:8in51infantswereappliedtreatmentfor2month,12were5months,17were7months,14were9mont
6、hsinfants.Hemangiomasofchildrenareall5萬方數(shù)據(jù)福建醫(yī)科大學2009級碩士學位論文stopgrowthwiththesizeissmaller,textureismoresoftaftertreatment.PSVislowerandRIisincreasein25cases(P<0.05).TheoverallresponsewasscaleI(poor)in4patient(7.84%),scaleII(moderate)in18patients(35.29%),scaleШ(good)in22patients(43.14%)andscaleIV
7、(excellent)in7patients(13.73%).Thechangesinsuperficialhemangiomawasbetterthanothers(P<0.05).Thereisnosignificantdifferentinlocated(P>0.05).Childreninthefollow-upprocessdoesnotappearobviousheartrate,bloodpressureandfastingblo