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1、1提高感染疾病的診治水平-----關(guān)注CLSI血培養(yǎng)指南王瑤北京協(xié)和醫(yī)院檢驗(yàn)科臨床微生物專(zhuān)業(yè)組MakeempiricaltherapymoreeffectivePatient?Etiology?Resistance?cipamk全球關(guān)注的多重耐藥菌產(chǎn)ESBL的腸桿菌科菌產(chǎn)KPC的腸桿菌科菌MRSAVREMDRPACRABAPUMCH痰標(biāo)本前10位的菌株OrganismNumber%Acinetobacterbaumannii45521Pseudomonasaeruginosa36416Staphy.aureus26112Kl
2、eb.pneumoniae1718Candidaalbicans1436Escherichiacoli1065Steno.maltophilia1025Enterobactercloacae583Haemophilusinfluenzae412Enterococcusfaecalis382呼吸道痰標(biāo)本分離的471株鮑曼不動(dòng)桿菌的耐藥性分析Antibioticname%R%I%SMinocycline31.824.843.3Cefoperazone/Sulbactam49.925.924.2Imipenem69.31.928.
3、8Meropenem72.40.826.8Levofloxacin73.36.420.3Ampicillin/Sulbactam75.23.921Amikacin77.31.321.4Cefepime77.92.519.5Piperacillin/Tazobactam78.15.116.8Ciprofloxacin800.619.4Trimethoprim/Sulfamethoxazole80.30.619Ceftazidime80.68.111.3PUMCH:痰涂片染色鏡檢PUMCH尿液標(biāo)本前10位的菌株OrganismN
4、um.%Escherichiacoli20834Enterococcusfaecalis6310Pseudomonasaeruginosa417Klebpneumoniae396Enterococcusfaecium335Candidaalbicans264Acinetobacterbaumannii203Staphylococcus,coagulasenegative193Staphylococcusaureus173Torulopsis(Cand.)glabrata142尿路感染分離的215株大腸桿菌的耐藥性Antibi
5、oticname%R%I%SImipenem0.00.0100Meropenem0.00.0100Ertapenem0.50.099.5Piperacillin/Tazobactam3.34.792.1Cefoperazone/Sulbactam5.618.775.7Minocycline45.31638.7Cefepime60.50.039.5Cefotaxime60.61.438.0Ceftriaxone60.70.039.3Ceftazidime60.90.039.1Trimethoprim/Sulfamethoxaz
6、ole73.32.424.3Levofloxacin77.63.718.7Ciprofloxacin81.40.917.7PUMCH血流感染前10位的菌株OrganismNum.%Staphy.coagulasenegative17225Escherichiacoli10215Acinetobacterbaumannii538Staphylococcusaureus416Enterococcusfaecium396Pseudomonasaeruginosa355Enterococcusfaecalis325Klebsiell
7、apneumoniae325Candidaalbicans122Enterobactercloacae81PUMCH插管前10位的菌株OrganismNum%Staphy.,co.negative1521Escherichiacoli1014Acinetobacterbaumannii710Staphylococcusaureus68Enterococcusfaecalis68Pseudomonasaeruginosa57Staphylococcusepidermidis46Candidaspp46Burkholderiac
8、epacia23Klebsiellaoxytoca232010年CLSI修改了頭孢菌素和單環(huán)類(lèi)對(duì)腸桿菌科的BP抗菌藥物紙片擴(kuò)散法(mm)瓊脂稀釋法(μg/ml)2009年2010年2009年2010年頭孢他啶R≤14S≥18R≤17S≥21S≤8R>=32S≤4R≥16頭孢噻肟R≤14S≥