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《CT灌注成像評價經(jīng)導(dǎo)管動脈化療栓塞術(shù)治療原發(fā)性肝癌的療效-論文.pdf》由會員上傳分享,免費在線閱讀,更多相關(guān)內(nèi)容在應(yīng)用文檔-天天文庫。
1、中國介入影像與治療學(xué)2013年第10卷第12期ChinJIntervImagingTher,2013,Vol10,No12EvaluationoftherapeuticeffectoftranscatheterarterialchemoembolizationforprimaryhepaticcarcinomawithCTperfusionimagingQIUGuo—qin,XULi—zhen,CHENYu—qiang,LJUChang—hua(CancerCenter,ChenggongHospital
2、Al;tliatedtoXiamenUniversity,the174thHospitaloftheChinesePeople'sLiberationArmy,Xiamen361003,China)[Abstract]0bjectiveToexplorethevalueofcTperfusionimaging(CTPI)using320一rOWcTscannerinevaluationonthetherapeuticeffectofTACEforprimarylivercancer(PHC).Method
3、sTotally91patientswithadvancedPHCunder—wentCTPIbeforeandafterTACE.ComparedwiththeresultofDSA,bloodperfusionchangesoftumorandnormalliverwereobserved,andthecurativeeffectofTACEwasevaluated.ResultsCTPIcorrespondedwithDSA。thediagnosticcO—incidencerateofCTP1wa
4、s100.Bloodflow(BF),bloodvolume(BV),hepaticarteria1persusion(HAP)andhepaticperfusionindex(HPI)oftumortissuedecreasedafterTACE(allP<0.05),whilenostatisticallysignificantdifferenceofmeantransittime(MTT),probabilityofsurfaceareaproduct(PS)norportalveinperfusi
5、on(PVP)oftumortissuewasfoundbeforeandafterTACE(allP>0.05).Unevenmelanomafocaliodineoildepositsandbloodperfusionwereshowedin59caseswithresidua1tumortissue,withBF,BV,HAP,HPI,PSofresidualtumortissuehigherbutMTTandPVPlowerthanthosenormalhepatictissue(allP<0.0
6、5).ConclusionCTPIusing320一rOWCTscannercancomprehensively.derectlyandquantificationallyreflectthehemodynamicchangesofPHCbeforeandafterTACE,thereforeobjectivelyandcorrectlyevaluatingtheeffectofTACE.[Keywords]Liverneoplasms;Perfusionimaging;Tomography,x—rayc
7、omputedCT灌注成像評價經(jīng)導(dǎo)管動脈化療栓塞術(shù)治療原發(fā)性肝癌的療效邱國欽,許麗貞,陳玉強,劉昌華(廈門大學(xué)附屬成功醫(yī)院中國人民解放軍第174醫(yī)院腫瘤中心,福建廈門361003)[摘要]目的探討320排CT灌注成像(CTPI)評價TACE治療原發(fā)性肝癌(PHC)療效的價值。方法對91例中晚期PHC患者于TACE治療前后行CTPI,對比DSA結(jié)果,觀察TACE前后腫瘤與正常肝組織的血流灌注參數(shù)的變化,評價TACE療效。結(jié)果CTPI診斷結(jié)果與DSA結(jié)果相符,診斷符合率為100,TACE后腫瘤組織的肝血流量(
8、BF)、肝血容量(BV)、肝動脈灌注量(HAP)、肝動脈灌注指數(shù)(HPI)均較術(shù)前降低(P均o.05);59例瘤灶碘油沉積不均,灌注圖顯示存在血流灌注,其殘瘤組織的BF、BV、HAP、HPI、PS值均高于正常肝組織(P均