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1、一38一介入放射學雜志2014年1月第23卷第1期JInterventRadiol2014,V0l-23,N0.1·非血管介入Non.vascularintervention·經皮肝穿刺微波治療肝癌的嚴重并發(fā)癥18例分析胡清雯,錢國軍【摘要】目的分析經皮肝穿刺微波熱凝毀損肝癌治療的嚴重并發(fā)癥及其預防和治療措施。方法2010年1月一2011年12月,對經臨床或病理證實為原發(fā)或轉移性肝癌的患者共進行了3419例次經皮肝穿刺微波術治療肝癌。所有患者術后均定期隨訪,了解與手術相關的近期及遠期并發(fā)癥的發(fā)生與愈后。結果共發(fā)生嚴重并發(fā)癥18例,包括腹腔出血1例,腸瘺1例,膽道損傷3例,急性腎衰竭1
2、例,感染12例。其中因并發(fā)癥死亡3例。嚴重并發(fā)癥發(fā)生率0.53%(18/3419),并發(fā)癥相關病死率16.7%(3/18)。結論經皮肝穿刺微波熱凝毀損肝癌治療術對于肝腫瘤部位相對復雜或特殊、凝血機制及全身情況較差者,仍存在有較大的風險。須嚴格掌握適應證,術前應有針對性的對癥治療及術前準備,術中規(guī)范及精準的經皮肝穿刺操作,術后嚴密觀察病情變化,其中有些并發(fā)癥可以防治,有些可以及早發(fā)現(xiàn)并獲得積極救治,減少并發(fā)癥所導致的相關病死率及其不良影響【關鍵詞】肝癌;微波;并發(fā)癥中圖分類號:R735.7文獻標志碼:A文章編號:1008—794X(2014)一01.0o38.04Severecompl
3、icationsofpercutaneousmicrowavecoagulationtherapyforhepaticmalignancy:ananalysisof18casesHUQing-wen,QIANGuo—jun.DepartmentofMinimalInvasionTherapy,theAfiliatedEasternHepatobiliralySurgeryHospital,theSecondMilitaryMedicalUniversity,Shanghai2oo438.ChinaCorrespondingauthor:QIANGuo-jun,E—mail:q@sin
4、a.com【Abstract】ObjectiveToanalyzethecause,preventionandtreatmentofseverecomplicationsofpercutaneousmicrowavecoagulationtherapy(PMCT)forhepaticmalignancy.MethodsDuringtheperiodfromJan.2010toDec.2011.atotalof3419proceduresofPMCTwerecarriedoutinauthors’hospitalforpatientswithpathologically—orclini
5、cally—confirmedhepaticcarcinomaorhepaticmetastasis.Allthepatientswereperiodically~llowedup.Theprocedure·relatedandshort—to—long—termcomplicationswererecorded.Theresultswereanalyzed.ResultsSeverecomplicationsoccurredin18patients,whichincludedintra—abdominalhemorhage(n=1),bowelleakage(n=1),biledu
6、ctinjury(n=3),acuterenalfailure(n=1)andinfection(n=12).Threepatientsdiedofaboveseverecomplications.Theincidenceofcomplicationwas0.53%(18/3419)andthecomplication—relatedmortalitywas16.67%(3/18).ConclusionAlthoughPMCTisaminimallyinvasivetechnique,itstillcarriesrisksforpatientswithinsuficientblood
7、coagulationandpoorclinicalconditionorforpatientswiththetumorbeinglocatedattheunusualregions.Theindicationsshouldbestrictlyobserved.Carefulperioperativepreventionmeasures,closeobservationafterthetreatmentandearlydetectionofcomplica